Transdisciplinary Cancer Control Research Training Grant

描述（由申请人提供）：这是我们R25T项目的竞争性续期申请。我们的R25T的具体目标是为培养下一代癌症预防和控制的跨学科研究人员做出贡献-这些人既可以成为PI团队的领导者，也可以成为共同研究的合作者。我们的目标是在完成最初的单一学科博士后培训后的三年内提供早期职业，跨学科培训。因此，在完成我们的R25T后，学员将在4-6年之间的研究生阶段，并理想地定位于响应当前的跨学科NIH路线图倡议，在NCI认为“非凡”机会的领域获得资助，并解决21世纪新发现的癌症控制问题。我们的R25T培训计划是基于布朗大学三个主要项目的个人优势和合作的协同作用：(a)行为和预防医学中心；(b)老年学和保健研究中心；(c)布朗大学肿瘤小组。此外，布朗大学不断壮大的公共卫生项目已经并将继续成为公共卫生硕士课程的重要资源，并为受训者提供人口层面的癌症控制视角。在这个更新周期中，我们将继续提供和完善癌症预防和控制的跨学科研究课程，提供共同共享培训和个性化研究培训的平衡。个性化培训计划包括：1)监督参与已建立的研究团队的正在进行的工作，一个由主要导师领导，另一个由至少一名来自其他学科的第二导师领导；2)参加布朗大学公共卫生硕士项目，选择课程或获得完整学位；3)参与创新教学，包括互动式跨学科研讨会和肺癌跨学科方法研讨会；4)正式的拨款写作指导，以制定和提交跨学科癌症预防和控制的R01或同等拨款。我们的R25T培训在现有的T32博士前和博士后培训项目的基础上，通过弥合学科之间的差距，并提供额外的三年指导早期职业支持，填补了布朗大学的独特需求。

DESCRIPTION (provided by applicant): This is a competitive renewal application of our R25T program. The Specific Aims of our R25T are to contribute to the training of the next generation of transdisciplinary researchers in cancer prevention and control - persons who can be both PI team-leaders and also co-investigator collaborators. Our objective is to provide early career, transdisciplinary training for the three years following completion of an initial single- discipline, postdoctoral traineeship. Thus, upon completion of our R25T, trainees will be between 4-6 years postgraduate and ideally positioned to respond to current transdisciplinary NIH Roadmap initiatives, to obtain funding in areas considered "extraordinary" opportunities by NCI, and to address newly identified cancer control issues that emerge as the 21st century proceeds. Our R25T training program is based on the individual strengths of, and the synergy of cooperation among, three major programs at Brown: (a) The Centers for Behavioral and Preventive Medicine; (b) The Center for Gerontology and Healthcare Research; and (c) The Brown University Oncology Group. In addition, the growing Program in Public Health at Brown has been, and will continue to be, a significant resource for MPH coursework and providing trainees with a population-level perspective on cancer control. In this renewal cycle, we will continue delivering, and refine, a curriculum in transdisciplinary research for cancer prevention and control that provides a balance of in- common shared training and individualized research training. The individualized training plan includes: 1) supervised participation in the ongoing work of established research teams, one led by a primary mentor and the other by at least one other second mentor from another discipline; 2) participation in Brown's MPH program either with selected coursework or matriculation for the full degree; 3) participation in innovative didactics, including an interactive transdisciplinary seminar and a seminar on transdisciplinary approaches to lung cancer; and 4) formal instruction in grant writing leading to the development and submission of an R01 or equivalent grant in transdisciplinary cancer prevention and control. Our R25T training fills a unique need at Brown by building on existing T32 predoctoral and postdoctoral training programs, by bridging the gap between disciplines, and providing an additional three years of mentored early career support.