Affymetrix GeneChip Scanner 3000 System

Affymetrix GeneChip 扫描仪 3000 系统

• 批准号: 6878157
• 负责人: Francisco Martinez-Murillo
• 金额: $ 22.08万
• 依托单位: JOHNS HOPKINS UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2005
• 资助国家: 美国
• 起止时间: 2005-01-01 至 2005-12-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6878157
• 关键词: DNA; biomedical equipment purchase; biotechnology; microarray technology; molecular genetics

DESCRIPTION (provided by applicant): We request an Affymetrix GeneChip Scanner 3000 System to complete our state of the art microarray core facility at the Johns Hopkins University School of Medicine. This system is the only piece of equipment that allows the processing and scanning of Affymetrix's new high density GeneChip arrays, which contain comprehensive whole-genome information for the human, murine, or rat genomes in a single microarray. The scanner offers advanced design improvements of speed, minimization of space, and automation of microarray scanning procedures. It provides a consistent scanner-to-scanner overall biological performance, improving data integrity and very importantly, consistent data sharing between researchers. The accessories of the scanner included in this proposal are a workstation, with the new software and new operating system, a 48-array scanner autoloader carrousel, and a fluidics station to support the high microarray throughput processed at the microarray core. These accessories are needed for the full operability of the scanner at the core. This scanner will be located in our centralized core facility within the basic sciences and will be supervised and maintained by our expert and experienced microarray core staff and management. The system will serve a large NIH-funded scientific community of over 130 users from multiple departments throughout the Johns Hopkins University.

描述（由申请人提供）：我们请求使用Affyscore基因芯片扫描仪3000系统来完成我们在约翰霍普金斯大学医学院的最先进的微阵列核心设施。该系统是唯一一款允许处理和扫描Affyoung新的高密度基因芯片阵列的设备，该阵列在单个微阵列中包含人类，小鼠或大鼠基因组的全面全基因组信息。该扫描仪提供了先进的设计改进的速度，最小化的空间，和自动化的微阵列扫描程序。它提供了一致的扫描仪到扫描仪的整体生物性能，提高了数据完整性，非常重要的是，研究人员之间的一致数据共享。本提案中包括的扫描仪附件是一个工作站，具有新的软件和新的操作系统，一个48阵列扫描仪自动装载机转盘，以及一个流体站，以支持在微阵列核心处理的高微阵列通量。这些附件是扫描仪在核心的全面可操作性所必需的。这台扫描仪将位于我们的基础科学中心核心设施内，并将由我们的专家和经验丰富的微阵列核心工作人员和管理人员监督和维护。该系统将服务于一个由NIH资助的大型科学社区，该社区由来自约翰霍普金斯大学多个部门的130多名用户组成。