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Single Chain Antibody Core

Single Chain Antibody Core
单链抗体核心
批准号:
6942229
负责人:
Bryan R. G. Williams
金额:
$6.77万
依托单位国家:
美国
项目类别:
财政年份:
2004
资助国家:
美国
项目状态:
已结题
起止时间:
2004-07-12 至 2010-03-31

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中文摘要
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英文摘要
This core will develop highly selective, high affinity antibodies to investigate coordinated cell signaling. Antibodies will be generated to distinguish active forms of target enzymes. The antibodies will be isolated from an established cDNA, single-chain immune library displayed on ribosomes. This library will be screened using modified peptides that mimic the effector regions of key signal proteins or, alternatively, fulllength activated proteins. This objective will be fulfilled in two specific aims: 1. To maintain immune libraries, 2. To isolate single-chain antibodies to specific antigens.
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INTEGRATED PROTEOM WORKS SYSTEM: CANCER, PROSTATE & BREAST CANCER
  • 批准号:
    7166142
  • 项目类别:
  • 资助金额:
    $5.59万
  • 财政年份:
    2005
  • 负责人:
    Bryan R. G. Williams
  • 依托单位:
INTEGRATED PROTEOM WORKS SYSTEM: CARDIOVASCULAR DISEASE
  • 批准号:
    7166141
  • 项目类别:
  • 资助金额:
    $10.07万
  • 财政年份:
    2005
  • 负责人:
    Bryan R. G. Williams
  • 依托单位:
INTEGRATED PROTEOM WORKS SYSTEM: ASTHMA, IMMUNOLOGY
  • 批准号:
    7166143
  • 项目类别:
  • 资助金额:
    $6.71万
  • 财政年份:
    2005
  • 负责人:
    Bryan R. G. Williams
  • 依托单位:
Pilot: Regulation of Obesity and ER Stress by Salicylates
  • 批准号:
    7007855
  • 项目类别:
  • 资助金额:
    $25.0万
  • 财政年份:
    2005
  • 负责人:
    Bryan R. G. Williams
  • 依托单位:
海外基金