Reliable/Safe Laser Pointing-People Locked-in Syndrome

可靠/安全的激光指向-人员锁定综合症

• 批准号: 7110062
• 负责人: THOMAS JAKOBS
• 金额: $ 9.72万
• 依托单位: INVOTEK, INC.
• 依托单位国家: 美国
• 财政年份: 2006
• 资助国家: 美国
• 起止时间: 2006-05-01 至 2007-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7110062
• 关键词: assistive device /technology; bioengineering /biomedical engineering; clinical research; clinical trials; functional ability; human subject; human therapy evaluation; lasers; medical rehabilitation related tag; patient oriented research; photoconduction; portable biomedical equipment; rehabilitation; technology /technique development

DESCRIPTION (provided by applicant): The proposed project enables people with very limited movement to use a laser to control assistive devices - safely. This Phase 1 Fast-Track research focuses on developing a custom, low-cost, photosensitive material that detects the light from a laser. The fundamental scientific knowledge gained during Phase 1 will enable the research team to manufacture laser-sensing surfaces reliably. The goal for Phase 1 is to produce, without failure, five laser-sensing surfaces with a signal-to-noise ratio of at least 3:1. The Phase 2 Fast-Track research focuses on demonstrating the reliability, safety, and efficacy of the Safe- laser Pointing System for individuals with Locked-in Syndrome by completing three major tasks. First, the technical team will continue its work by optimizing the laser-sensing surface developed in Phase 1 and producing reliable prototypes for clinical evaluation. Second, we must design a Safe-laser pointer that is lightweight, and easy to wear and point. Third, individuals with Locked-in Syndrome (LIS), their families, and the professionals that care for them will comprehensively evaluate these prototypes over an 18-month clinical study. This evaluation will demonstrate the reliability and safety of the prototypes, and the efficacy of the Safe-laser Pointing System for meeting the assistive technology needs of the underserved LIS population, both from the perspective of training assistive technology use and successfully integrating technology into their lives. The Safe-laser Pointing System is an important, innovative, access method for a wide range of disability etiologies, including cerebral palsy, amyotrophic lateral sclerosis, brainstem stroke, traumatic brain injury, and myasthenia gravis. It enables many people with restricted movement to achieve direct access control of electronic technology and avoid the use of single-switch scanning. Upon completion of this research, we will implement a well-conceived and swift commercialization plan to make this technology available to the people that need it.

描述（由申请人提供）：拟议的项目使运动非常有限的人可以安全地控制辅助设备。这一阶段1快速轨道研究重点是开发一种定制的低成本光敏材料，该材料检测到激光器的光。在第1阶段获得的基本科学知识将使研究团队能够可靠地生产激光表面。第1阶段的目标是在没有故障的情况下产生五个激光表面，信噪比至少为3：1。第2阶段快速轨道研究的重点是通过完成三项主要任务来证明安全激光指向系统对患有锁定综合征的个体的安全性，安全性和功效。首先，技术团队将通过优化在第1阶段开发的激光表面并生产可靠的原型来继续进行临床评估，以继续其工作。其次，我们必须设计一个轻巧且易于穿着和指向的安全激光指针。第三，患有锁定综合征（LIS）的人，他们的家人以及关心他们的专业人员将在18个月的临床研究中全面评估这些原型。该评估将证明原型的可靠性和安全性，以及安全激光指向系统在满足服务不足的LIS人群的辅助技术需求方面的功效，既是从培训辅助技术的角度来看，又可以成功地将技术整合到他们的生活中。安全激光指向系统是多种残疾病因的重要，创新的，访问方法，包括脑瘫，肌萎缩性侧面硬化症，脑干中风，脑部创伤性脑损伤和肌无力。它使许多受限制运动的人能够直接访问电子技术，并避免使用单切换扫描。这项研究完成后，我们将实施一个构思良好且迅速的商业化计划，使这项技术可用于需要它的人们。