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Discovery

Discovery
发现
批准号：
7195621
负责人：
Joan Siefert Brugge
金额：
$14.59万
依托单位：
UNIVERSITY OF VIRGINIA
依托单位国家：
美国
项目类别：
财政年份：
2006
资助国家：
美国
项目状态：
已结题
起止时间：
2006-08-01 至 2011-07-31
来源：
https://reporter.nih.gov/project-details/7195621
关键词：
DrosophilidaeRNA interferencebiomedical facilitycell adhesioncell biologycell migrationcell morphologycell motilitycooperative studygene expressionhelminth geneticshigh throughput technologyprotein localization

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中文摘要
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英文摘要
The overall goal of this Initiative is to expand the current Migration Knowledgebase through the identification of cellular genes that regulate cell shape, adhesion and motility using high throughput RNA interference screens in cell- or organism-based assays. In addition, large scale expression screens will be employed in the fruit fly to identify candidate genes that display patterns of expression and intracellular localization consistent with a role in migration. Through coordinated cross-species analyses we will identify a set of genes that play a central and conserved role in cell adhesion and migration.
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  • 财政年份：
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  • 依托单位：
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