Insulating Coatings for Implant Devices & Ribbon Cables

植入设备的绝缘涂层

• 批准号: 6896142
• 负责人: Helmut Eckhardt
• 金额: $ 34.56万
• 依托单位: PREMITEC, INC.
• 依托单位国家: 美国
• 财政年份: 2000
• 资助国家: 美国
• 起止时间: 2000-11-01 至 2006-09-29
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6896142
• 关键词: biomaterial compatibility; biomaterial development /preparation; biomaterial interface interaction; dogs; electrical impedance; electrical potential; electrochemistry; electrodes; electroretinography; electrostimulus; eye fundus photography; histology; implant; iridium; medical implant science; metal oxide; nervous system prosthesis; optical tomography; platinum; retina; surface coating

DESCRIPTION (provided by applicant): We propose the development of a novel flexible integrated microelectrode array as active stimulating interface to the neural system in the retina of the human eye. Our approach, in which microelectrode arrays, interconnecting leads and circuitry traces are embedded and integrated on a single flexible polyimide foil and encapsulated with our proprietary materials will overcome the classical separation of substrate and insulation layers, a weak point in many biomedical implant devices. To achieve this goal we will combine our proprietary A-Coat TM encapsulation technology for flex substrates with our proprietary metal-to-flex substrate adhesion technology. This implant device promises to deliver improved long-term performance under stimulating pulsed conditions and excellent long-term biocompatibility.

描述（由申请人提供）：我们提出开发一种新型柔性集成微电极阵列，作为人眼视网膜神经系统的主动刺激界面。我们的方法，其中微电极阵列，互连引线和电路迹线嵌入和集成在一个单一的柔性聚酰亚胺箔，并与我们的专有材料封装将克服经典的分离基板和绝缘层，在许多生物医学植入设备的弱点。为了实现这一目标，我们将联合收割机结合我们专有的A-Coat TM封装技术与我们专有的金属-柔性基板粘合技术。该植入器械有望在刺激脉冲条件下提供改善的长期性能和出色的长期生物相容性。