TULANE NATINAL PRIMATE RESEARCH CENTER

超出空间 提供了 该申请要求为杜兰国家灵长类动物研究中心（TNPRC）提供五年的资金 从2003年5月1日到2008年4月30日。资金将用于支持行政管理， 中心的业务、兽医资源和科研资源。额外资金支持 还要求开展试点研究项目和与蜂群健康有关的研究资源项目。 TNPRC的研究计划专注于传染病研究近三年 几十年虽然该中心的大部分研究工作都致力于传染病，但 基因治疗和辅助生殖技术的项目也在迅速扩大。传染 目前，该项目的重点是艾滋病、疟疾、微孢子虫病和莱姆病。这些是 多学科研究，涉及TNPRC多个部门的研究人员和合作者 中心外。这些研究涵盖了从传播、诊断和发病机制到 疫苗策略和化疗治疗的发展，以及从病理损伤到基因 序列的此外，基因治疗计划的发展允许新的方法来治疗癌症。 许多类型疾病的治疗和各种基因治疗模式的临床前建模。 在过去的五年里，特别是去年，该中心发生了重大变化， Peter Gerone博士退休，Andrew Lackner博士被任命为新主任。自10月1日起， 2001年，Lackner博士成为主任，几个部门的领导层发生了变化，新的部门 已经成立，业务办公室（现为行政事务处）已开始重组。的 结果是一个中心，现在更加重视研究计划，并经历了50%的 其赠款组合的增长。这些变化是由一个非常乐于助人和合议主持人促成的 机构。TNPRC的新组织结构和领导团队以及最近在 获得赠款资金和吸引外部合作表明，该中心准备在一段时间内， 显著增长和改善。

EXCEED THE SPACE PROVIDED. This application requests funding for the Tulane National Primate Research Center (TNPRC) for the five year period beginning May 1, 2003 through April 30, 2008. Funds will be used to support the administration, operations, veterinary resources, and scientific research resources of the Center. Additional funds to support pilot research projects and colony-health-related research resource projects are also requested. The research program at the TNPRC has been focused on infectious disease research for close to three decades. Although the majority of the Center' s research efforts are devoted to infectious disease, there are also rapidly expanding programs in gene therapy and assisted reproductive technologies. The infectious disease program currently focuses on AIDS, Malaria Microsporidial diseases and Lyme disease. These are multidisciplinary studies involving investigators in- numerous Divisions at the TNPRC and collaborators outside the Center. The studies cover the spectrum from transmission, diagnosis and pathogenesis to development of vaccine strategies and chemotherapeutic treatments, and from pathologic lesions to gene sequences. In addition, the development of the gene therapy program allows for novel approaches to the treatment of many types of disease and preclinical modeling of a variety of gene therapy modalities. The last five years and particularly the last year have seen significant changes at the Center, following the retirement of Dr. Peter Gerone and the naming of Dr. Andrew Lackner as the new Director. Since October 1, 2001 when Dr. Lackner became Director, leadership in several of the divisions has changed, new divisions have been formed and the business office (now Administrative Services) has begun reorganization. The result is a Center that now places more emphasis on research programs and which has experienced a 50% growth in its grant portfolio. These changes have been facilitated by a very helpful and collegial host institution. The new organizational structure and leadership team at the TNPRC and recent successes in obtaining grant funding and attracting outside collaboration suggest that the Center is poised for a period of significant growth and improvement.