Towards a molecular understanding of Mucorales-bacterial interactions underpinning disease

对导致疾病的毛霉目-细菌相互作用的分子理解

• 批准号: 2868750
• 金额: --
• 依托单位: UNIVERSITY OF EXETER
• 依托单位国家: 英国
• 项目类别: Studentship
• 财政年份: 2022
• 资助国家: 英国
• 起止时间: 2022 至 无数据
• 项目状态: 未结题
• 来源: https://gtr.ukri.org/projects?ref=studentship-2868750
• 关键词: Towards; molecular; understanding; Mucorales; bacterial

Mucorales are soil-dwelling fungal pathogens that can infect immunocompromised patients, yet many questions remain about their basic biology and modes of growth. In this project, the student will develop tools to better understand the genetic networks that regulate fungal growth, stress resistance, and pathogenesis, with the long term goal of improving our ability to study the molecular mechanisms underpinning the capacity of these organisms to cause devestating disease.

Mucorales是一种居住在土壤中的真菌病原体，可以感染免疫功能低下的患者，但关于其基本生物学和生长模式仍有许多问题。在这个项目中，学生将开发工具来更好地了解调节真菌生长，抗逆性和发病机制的遗传网络，其长期目标是提高我们研究这些生物体导致破坏性疾病的能力的分子机制的能力。