TULANE CANCER GENETICS COBRE: ATR KINASE AND UV-INDUCED CELL CYCLE CHECKPOINTS

杜兰大学癌症遗传学 COBRE：ATR 激酶和紫外线诱导的细胞周期检查点

• 批准号: 7171364
• 负责人: BO XU
• 金额: $ 26.5万
• 依托单位: TULANE UNIVERSITY OF LOUISIANA
• 依托单位国家: 美国
• 财政年份: 2005
• 资助国家: 美国
• 起止时间: 2005-08-01 至 2006-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7171364
• 关键词: genetic regulation; neoplasm /cancer genetics

DESCRIPTION (provided by applicant): This COBRE is designed to develop the research careers of a series of promising junior investigators in the field of Cancer Genetics. Their careers will be developed utilizing a strong core of research mentors who will help craft a plan for the development of each investigator, and provide advice and encouragement to those investigators. The five projects in this COBRE focus on two critical, overlapping areas in cancer genetics, genetic instability and gene regulation. An internal advisory committee composed of mentors and other scientists with extremely strong research and mentoring records, along with a prominent board of external advisors with outstanding research careers and track records of career development for junior scientists, will participate not only in the guidance, but also the evaluation of progress of the junior investigators. Besides the strong mentoring program, career development will involve a series of program meetings, exposure to didactic grant-writing sessions, mini-symposia, and seminars to develop a highly collaborative environment for both the junior faculty, as well as other members of the COBRE and the Cancer Genetics Research Program under the auspices of the Louisiana Cancer Research Consortium (LCRC). The LCRC is a joint effort of Tulane University and the Louisiana State University Health Sciences Center in New Orleans to develop a Cancer Consortium. The Consortium is funded by a long-term State of Louisiana commitment, with the goal of obtaining NCI-designation for a Cancer Center in New Orleans. The Consortium is providing funds for recruitment of at least 6 new investigators for the Cancer Genetics Research Program in the next two years, as well as providing a new building that will allow investigators from both Tulane and LSUHSC to share common space designed around this Program. This COBRE will represent the ideal centerpiece to develop successful and productive careers of promising junior investigators who are valuable members of the Cancer Genetics Research Program, in a manner centered on collaboration and faculty development, resulting in strong growth and establishing long-term success of both the COBRE and the Cancer Genetics Research Program.

描述(由申请人提供)： 这一科布雷旨在发展癌症遗传学领域一系列有前途的初级研究人员的研究生涯。他们的职业生涯将利用强大的研究导师核心来发展，这些导师将帮助制定每个调查员的发展计划，并为这些调查员提供建议和鼓励。Cobre中的五个项目集中在癌症遗传学、遗传不稳定性和基因调控这两个关键的重叠领域。一个由导师和其他具有极强研究和辅导记录的科学家组成的内部咨询委员会，以及一个由具有杰出研究生涯和初级科学家职业发展记录的著名外部顾问组成的委员会，不仅将参与指导，还将参与对初级调查人员进展的评价。除了强大的指导计划外，职业发展还将包括一系列计划会议、授课拨款撰写会议、小型座谈会和研讨会，以为初级教员以及Cobre和路易斯安那州癌症研究联盟(LCRC)赞助的癌症遗传学研究计划的其他成员创造高度合作的环境。LCRC是杜兰大学和新奥尔良的路易斯安那州立大学健康科学中心共同努力发展的癌症联盟。该联盟由路易斯安那州的一项长期承诺资助，目标是获得新奥尔良癌症中心的NCI称号。该联盟将提供资金，用于在未来两年为癌症遗传学研究计划招募至少6名新的研究人员，并提供一座新建筑，使杜兰大学和LSUHSC的研究人员能够共享围绕该计划设计的公共空间。Cobre将是发展有前途的初级研究人员成功和富有成效的职业生涯的理想核心，他们是癌症遗传学研究计划的有价值的成员，以合作和师资发展为中心，导致Cobre和癌症遗传学研究计划的强劲增长和长期成功。