The development of salen-based artificial metalloenzymes for sustainable chemistry

人工金属酶（ArMs）将过渡金属反应性与酶的选择性相结合，将新的催化反应引入生物催化工具箱一类典型的过渡金属催化剂是salen和salophen型配合物，它们对一系列合成反应具有催化活性，包括环氧化、C-H键氧化和胺化、小分子活化（如水裂解）和绿色塑料的聚合反应。

Artificial metalloenzymes (ArMs) combine transition metal reactivity with the selectivity of enzymes to introduce new catalytic reactions into the biocatalytic toolbox.1 A classic group of transition metal catalysts are the salen and salophen-type complexes that exhibit catalytic activity for a range of synthetic reactions, including epoxidation, C-H bond oxidation and amination, small molecule activation such as water splitting, and polymerisation reactions for green plastics.