Molecular Mechanisms of Myofilaments Dysfunction in Heart Function

肌丝功能障碍影响心功能的分子机制

• 批准号: 7459534
• 负责人: Pieter P. de TOMBE
• 金额: $ 35.79万
• 依托单位: UNIVERSITY OF ILLINOIS AT CHICAGO
• 依托单位国家: 美国
• 财政年份: 2007
• 资助国家: 美国
• 起止时间: 2007-06-01 至 2010-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7459534
• 关键词: Address; Animals; Area; Award; Biochemical; Cardiac; Cardiac Myocytes; Characteristics; Chemicals; Chronic; Collaborations; Complement; Condition; Congestive Heart Failure; Contractile Proteins; Defect; Depressed mood; Development; Diffusion; Elements; Equilibrium; Experimental Models; Failure; Fiber; Financial compensation; Fistula; Functional disorder; Genetic Transcription; Goals; Grant; Heart; Heart Diseases; Heart Hypertrophy; Heart failure; Hypertrophy; Ions; Kinetics; Lead; Left Ventricular Hypertrophy; Link; Measures; Mechanics; Microfilaments; Modeling; Modification; Molecular; Muscle Cells; Myocardial Infarction; Myocardium; Myofibrils; Myosin ATPase; Paper; Phosphorylation; Preparation; Process; Property; Protein Biosynthesis; Protein Isoforms; Protein Kinase C; Protein Subunits; Proteins; Proteomics; Purpose; Rate; Rattus; Recombinant Proteins; Relaxation; Research; Rodent Model; Role; Sarcomeres; Secondary to; Signal Transduction; Site; Skin; Solutions; Staging; Takeda brand of pioglitazone hydrochloride; Techniques; Testing; Thin Filament; Transcriptional Activation; Translations; Troponin; Up-Regulation; Venous; Ventricular; Ventricular Dysfunction; Work; design; heart function; hemodynamics; in vivo; novel; pressure; programs; protein activation; protein function; research study; response; stressor