Neural Activity Shaping for Retinal and Cochlear Implants

视网膜和耳蜗植入物的神经活动塑造

• 批准号: DP140104533
• 负责人: Prof Anthony Burkitt
• 金额: $ 35.53万
• 依托单位: The University of Melbourne
• 依托单位国家: 澳大利亚
• 项目类别: Discovery Projects
• 财政年份: 2014
• 资助国家: 澳大利亚
• 起止时间: 2014-01-01 至 2017-12-31
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/DP140104533
• 关键词: Neural; Activity; Shaping; Retinal; Cochlear

This project aims to develop methods to control and optimise the spatial patterns of neural activity evoked by neural prostheses in order to improve the resolution of neuroprostheses. A major problem for neural prostheses is that the electrical current used to stimulate neurons causes a diffuse spread of activity in the neural tissue, which limits the resolution of the device. For patients this translates into limitations in sound quality, in the case of cochlea implants, or visual acuity, for retinal implants. The outcome of the project will be algorithms that optimally choose the currents on each electrode so as to shape neural activity at the finer resolution of electrode spacing rather than the coarser resolution of current spread.

该项目旨在开发控制和优化神经假体诱发的神经活动空间模式的方法，以提高神经假体的分辨率。神经假体的一个主要问题是用于刺激神经元的电流导致神经组织中的活动扩散，这限制了设备的分辨率。对于患者来说，这意味着声音质量（对于人工耳蜗植入物）或视力（对于视网膜植入物）的限制。该项目的成果将是最佳选择每个电极上的电流的算法，以便以电极间距的更精细分辨率而不是电流分布的更粗糙分辨率来塑造神经活动。