THE ROLE OF FEMALE REPRODUCTIVE HORMONES IN THE ETIOPATHOGENESIS OF TMJ DISEASES

女性生殖激素在颞下颌关节疾病发病机制中的作用

基本信息

  • 批准号:
    7202602
  • 负责人:
  • 金额:
    $ 0.19万
  • 依托单位:
  • 依托单位国家:
    美国
  • 项目类别:
  • 财政年份:
    2005
  • 资助国家:
    美国
  • 起止时间:
    2005-04-01 至 2006-03-31
  • 项目状态:
    已结题

项目摘要

DESCRIPTION (provided by applicant): We have now completed three years of a four-year cycle. The primary aim of the new program direction team of the GCRC during this time was to address shortcomings identified in previous reviews and to continue to build our program for the future. We have completed the renovation of our inpatient unit and now have a state-of-the-art facility to conduct clinical research. We have relocated our Core Laboratory to new, updated and convenient space near the inpatient unit. We have improved our productivity in all spheres of activity, with steady growth in number of A days and visits, number of protocols, number and diversity of investigators, increased number of medical students and post-doctoral trainees on the unit and expansion of the scope of training activities. This has been accompanied by a substantial increase in publication productivity by GCRC investigators. Our new Research Subject Advocate (RSA) program has played an important role in assisting and educating GCRC investigators in the areas of research subject consent, safety monitoring and regualtory compliance. The Core Laboratory expanded its services in genomics and other DNA technologies, and our new Exercise Physiology and Body Composition Laboratory has been providing services to a growing number of investigators. The level of activiy and excitement on the GCRC has never been higher. In this competing renewal proposal, 66 different principal investigators will perform 89 protocols in several areas including genetic epidemiology of connective tissue diseases and other disorders, pharmacogenetics, dementia research, gene expression profiling in cancer, HIV natural history and pathogenesis, exercise physiology in chronic diseases, and metabolic research with an emphasis on pathogenesis and treatment obesity, hypertension, bone loss and diabetes mellitus. These complement several other already active programs including oncology and psychopharmacology of drug addiction. These areas cover many of the emerging critical health issues as the population ages. Our focus over the next 5 years will be to continue to expand training on the GCRC; continue to expand our protocol diversity; and invest in and expand new laboratory and informatics technologies to allow the GCRC investigators to meet the research challenges of the future. To this end, we are requesting new resources to expand our services in database design, genomics capabilities and exercise physiology. As we do so, we will continue to perform this research with the highest standards of patient care, ethics, safety and regulatory compliance.
描述(由申请人提供):我们现在已经完成了四年周期中的三年。

项目成果

期刊论文数量(0)
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SUNIL D KAPILA其他文献

SUNIL D KAPILA的其他文献

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{{ truncateString('SUNIL D KAPILA', 18)}}的其他基金

Interdisciplinary Clinical Advances and Research Excellence in TMDs (ICARE 4 TMDs) Collaborative
TMD 跨学科临床进展和卓越研究 (ICARE 4 TMD) 协作
  • 批准号:
    10829180
  • 财政年份:
    2023
  • 资助金额:
    $ 0.19万
  • 项目类别:
Hormone-Receptor-MMP Axis in Degenerative TMJ Diseases
退行性颞下颌关节疾病中的激素-受体-MMP 轴
  • 批准号:
    7298758
  • 财政年份:
    2007
  • 资助金额:
    $ 0.19万
  • 项目类别:
Hormone-Receptor-MMP Axis in Degenerative TMJ Diseases
退行性颞下颌关节疾病中的激素-受体-MMP 轴
  • 批准号:
    7886563
  • 财政年份:
    2007
  • 资助金额:
    $ 0.19万
  • 项目类别:
Hormone-Receptor-MMP Axis in Degenerative TMJ Diseases
退行性颞下颌关节疾病中的激素-受体-MMP 轴
  • 批准号:
    7659648
  • 财政年份:
    2007
  • 资助金额:
    $ 0.19万
  • 项目类别:
Hormone-Receptor-MMP Axis in Degenerative TMJ Diseases
退行性颞下颌关节疾病中的激素-受体-MMP 轴
  • 批准号:
    8113279
  • 财政年份:
    2007
  • 资助金额:
    $ 0.19万
  • 项目类别:
Hormone-Receptor-MMP Axis in Degenerative TMJ Diseases
退行性颞下颌关节疾病中的激素-受体-MMP 轴
  • 批准号:
    7483118
  • 财政年份:
    2007
  • 资助金额:
    $ 0.19万
  • 项目类别:
Fibronectin Fragment-Induced Osteolysis Mediated by MMPs
MMP 介导的纤连蛋白片段诱导的骨溶解
  • 批准号:
    6910580
  • 财政年份:
    2005
  • 资助金额:
    $ 0.19万
  • 项目类别:
Fibronectin Fragment-Induced Osteolysis Mediated by MMPs
MMP 介导的纤连蛋白片段诱导的骨溶解
  • 批准号:
    7045964
  • 财政年份:
    2005
  • 资助金额:
    $ 0.19万
  • 项目类别:
Fibronectin Fragment-Induced Osteolysis Mediated by MMPs
MMP 介导的纤连蛋白片段诱导的骨溶解
  • 批准号:
    7587484
  • 财政年份:
    2005
  • 资助金额:
    $ 0.19万
  • 项目类别:
Fibronectin Fragment-Induced Osteolysis Mediated by MMPs
MMP 介导的纤连蛋白片段诱导的骨溶解
  • 批准号:
    7383934
  • 财政年份:
    2005
  • 资助金额:
    $ 0.19万
  • 项目类别:

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“当我爱我的上帝时,我爱什么呢?”:十四世纪末约克郡虔诚文化中的神圣人物和人类主体。
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  • 批准号:
    10360441
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  • 批准号:
    21K13658
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    2021
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