Generating killer cells for immunotherapy against cancer and pathogens

自然杀伤细胞（NK）和CD8+细胞毒性T淋巴细胞（CTL）通过杀死感染细胞内病原体和癌症的细胞来保护我们。该项目旨在利用最先进的技术（蛋白质组学、先进的流式细胞术）、独特的病毒库（腺病毒和巨细胞病毒）和临床样本（白血病）作为分析系统，找出驱动NK和CTL类型生长的原因，这些类型被优化为预防这些疾病。

Natural killer cells (NK) and CD8+ cytotoxic T lymphocytes (CTL) protect us by killing cells infected with intracellular pathogens and cancers. This project aims to work out what drives the growth of types of NK and CTL that are optimised to protect against these diseases, using state-of-the-art technologies (proteomics, advanced flow cytometry), unique libraries of viruses (adenovirus and cytomegalovirus) and clinical samples (leukaemias) as systems of analysis.