Elucidating conserved gene regulatory networks underlying plant immunity

至关重要的是，这个项目将确定我们的免疫基因网络在其他作物中的保守程度（测试芹菜和葫芦）。网络的保护将是一个重大的发现，因为它将为在这些作物中利用我们的网络发现开辟机会，而不必重复其基础的大规模数据生成。该学生将使用我们实验室现有的生菜基因编辑协议，以及与Tozer Seeds合作开发的其他作物的新基因编辑协议。这项工作将对未来的研究方法和我们操纵防御基因网络的能力产生重大的学术影响。

Crucially this project will determine to what extent our immunity gene network is conserved in other crops (testing celery and cucurbits). Conservation of the network would be a significant discovery as it would open-up opportunities for exploiting our network findings in these crops without having to repeat the large-scale data generation that underlies it. The student will use existing lettuce gene editing protocols in our lab and new gene editing protocols for other crops developed in a collaborative KTP with Tozer Seeds. The work would have major academic impact in terms of future research approaches and our ability to manipulate defence gene networks.