Design and Synthesis of New Chiral Heterogeneous Photocatalysts for Light-Driven Asymmetric Organocatalysis

光氧化还原催化是有机合成领域的重要发展，在温和条件下提供了不同的反应途径。进行具有对映体选择性的光氧化还原反应的能力尤为重要，这一点在2021年诺贝尔化学奖的获奖中得到了突出体现，以表彰不对称有机催化的发展。合成化学家可获得的大多数光催化剂是均相金属配合物或有机染料，这引起了成本、可回收性和废物产生的问题。多相有机光催化剂的开发可以解决这些问题，但其在有机合成中的应用还处于起步阶段。在本项目中，我们旨在设计和合成用于光驱动不对称有机催化的新型手性非均相光催化剂。

Photoredox catalysis is an important development in organic synthesis, offering distinct reaction pathways under mild conditions. The ability to perform photoredox reactions with enantioselectivity is particularly important, as highlighted by the award of the 2021 Nobel prize in Chemistry for the development of asymmetric organocatalysis. Most photocatalysts available to synthetic chemists are homogeneous metal-complexes or organic dyes, which raise issues of cost, recyclability, and waste production. Development of heterogeneous organic photocatalysts could address many of these issues but their application in organic synthesis is still in its infancy and underdeveloped. In this project we aim to design and synthesise new chiral heterogeneous photocatalysts for light-driven asymmetric organocatalysis.