Genetic influence on cognitive function and medication response in Attention Deficit Hyperactivity Disorder (ADHD).

遗传对注意力缺陷多动障碍（ADHD）认知功能和药物反应的影响。

• 批准号: nhmrc : 1004637
• 负责人: Dr Tim Silk
• 金额: $ 26.76万
• 依托单位: Murdoch Childrens Research Institute
• 依托单位国家: 澳大利亚
• 项目类别: Career Development Fellowships
• 财政年份: 2011
• 资助国家: 澳大利亚
• 起止时间: 2011-01-01 至 2014-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/genetic-influence-cognitive-disorder-adhd/109057
• 关键词: Genetic; influence; cognitive; function; medication

ADHD is one of the most common child mental health conditions, with cognitive deficits that impact everyday functioning, educational and social outcomes. Not all children with ADHD achieve equal benefit from medication. The disorder appears to be genetic with many genes contributing a small risk for the disorder. This project asks how DNA variation influences ADHD brain function and how they respond to medication. This project is important to improve the clinical diagnosis and outcome for ADHD.

ADHD是最常见的儿童心理健康状况之一，其认知缺陷会影响日常功能，教育和社会成果。并不是所有的ADHD儿童都能从药物治疗中获得同样的益处。这种疾病似乎是遗传性的，许多基因对这种疾病的风险很小。该项目询问DNA变异如何影响ADHD大脑功能以及它们对药物的反应。该项目对改善ADHD的临床诊断和结局具有重要意义。