2007 Mechanisms of Membrane Transport Gordon Conference

2007年膜传输机制戈登会议

• 批准号: 7272278
• 负责人: PETER C MALONEY
• 金额: $ 0.7万
• 依托单位: GORDON RESEARCH CONFERENCES
• 依托单位国家: 美国
• 财政年份: 2007
• 资助国家: 美国
• 起止时间: 2007-03-01 至 2008-02-29
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7272278
• 关键词: Area; Biochemistry and Pharmacology Cancer Activity; Biophysics; Cellular biology; Chromosome Pairing; Complex; Data; Discipline; Employee Strikes; Evaluation; Funding Applicant; Length; Membrane Proteins; Membrane Transport Proteins; Microbiology; Muscle; Nature; Nerve; Neurosciences; New Hampshire; Numbers; Optics; Pharmaceutical Preparations; Physiology; Pliability; Postdoctoral Fellow; Range; Recruitment Activity; Renal function; Research; Research Personnel; Resolution; Schools; Scientist; Signal Transduction; Structure; Students; Synapses; System; Techniques; Time; Transmembrane Transport; Work; base; insight; lectures; posters; programs; protein structure function; single molecule; symposium; transmission process

DESCRIPTION (provided by applicant): Funds are requested for support of the Gordon Research Conference entitled Mechanisms of Membrane Transport, to be held June 10-15, 2007, at Tilton School, Tilton, New Hampshire. This conference has met biannually for the past 40 years, largely focusing on areas related to the mechanistic aspects of membrane transport proteins. In 2007, we will continue to emphasize the striking advances and insights enabled by high-resolution structures of channels and transporters. We also focus on the most recent findings on other methods that reveal membrane protein structure and function, including areas such as NMR and analysis at the single-molecule level. Insights gained from such work now allows critical evaluation of mechanisms central to the functioning of renal and GI systems, the basis of excitability in muscle and nerve, signal transmission at nerve synapses, and extrusion of drugs. In addition to highlighting the timely and important advances, this conference will bring together scientists from a broad range of disciplines, promoting interactions that are otherwise difficult to establish. These fields include such areas as physiology, pharmacology, biochemistry, neuroscience, cell biology, microbiology, biophysics and optics. The program focuses closely on selected examples where high-resolution is now available (or soon will be) or where pre-existing structures have successfully been used to guide work in more complex examples. The conference will include 7 formal sessions that include 24 primary lectures, each of 30 minutes length, followed by sufficient time (15 minutes) for significant dialog with the audience. We are also devoting time on the podium (6 shorter presentations) to highlight the contributions of selected poster presenters, with an emphasis on new findings by students, postdoctoral fellows and young investigators. In addition, we are allowing time for open discussion of topical issues of a more controversial nature. As is our usual practice, we will encourage all attendees to bring posters of their latest work; based on historical data, this will allow for two poster sessions (Monday/Tuesday and Wednesday/Thursday) with 30-40 posters each. We have consciously selected a number of young investigators to present primary lectures, and have recruited a number of speakers who have not before attended this conference. Sufficient flexibility remains in the program to take advantage of late-breaking unanticipated findings with significant impact.

描述（由申请人提供）：资金要求支持戈登研究会议题为膜运输机制，将于2007年6月10日至15日，在蒂尔顿学校，蒂尔顿，新罕布什尔州。在过去的40年里，这个会议每半年举行一次，主要集中在与膜转运蛋白的机制方面有关的领域。2007年，我们将继续强调通道和转运体的高分辨率结构所带来的惊人进步和见解。我们还专注于揭示膜蛋白结构和功能的其他方法的最新发现，包括NMR和单分子水平分析等领域。从这些工作中获得的见解，现在允许关键的评价机制的核心功能的肾脏和胃肠道系统，在肌肉和神经的兴奋性，在神经突触的信号传输的基础，和挤出的药物。除了强调及时和重要的进展，这次会议将汇集来自广泛学科的科学家，促进否则难以建立的互动。这些领域包括生理学、药理学、生物化学、神经科学、细胞生物学、微生物学、生物物理学和光学。该计划密切关注选定的例子，其中高分辨率现在可用（或很快就会）或预先存在的结构已成功用于指导更复杂的例子中的工作。会议将包括7个正式会议，其中包括24个主要讲座，每个30分钟的长度，其次是足够的时间（15分钟）与观众进行重要对话。我们还在讲台上花时间（6个较短的演讲）来突出选定的海报主持人的贡献，重点是学生，博士后研究员和年轻研究人员的新发现。此外，我们也留出时间公开讨论更具争议性的议题。按照我们的惯例，我们将鼓励所有与会者携带他们最新作品的海报;根据历史数据，这将允许两个海报会议（周一/周二和周三/周四），每个海报30-40张。我们有意识地选择了一些年轻的研究人员来做主要的演讲，并招募了一些以前没有参加过这次会议的演讲者。该计划仍有足够的灵活性，以利用具有重大影响的最新意外发现。