Microevolution of Salmonella enterica serovar Typhimurium - molecular basis of emerging threats to human health

鼠伤寒沙门氏菌的微进化——人类健康新威胁的分子基础

• 批准号: 2893983
• 金额: --
• 依托单位: University of East Anglia
• 依托单位国家: 英国
• 项目类别: Studentship
• 财政年份: 2023
• 资助国家: 英国
• 起止时间: 2023 至 无数据
• 项目状态: 未结题
• 来源: https://gtr.ukri.org/projects?ref=studentship-2893983
• 关键词: Microevolution; Salmonella; enterica; serovar; Typhimurium

How and why do new strain variants of foodborne bacterial pathogens emerge and replace pre-existing strains? The answer to this question is important to intervening in the spread of the bacterial pathogen Salmonella within livestock and wild animals that are reservoirs of infection in people. The student will employ computational approaches to identify newly emerging strains of Salmonella and molecular biology to understand the consequences of microevolution on key characteristics associated with emergence.

食源性细菌病原体的新菌株变种如何以及为何出现并取代现有菌株？这个问题的答案对于干预细菌病原体沙门氏菌在作为人类感染宿主的牲畜和野生动物体内的传播非常重要。学生将利用计算方法来识别新出现的沙门氏菌菌株，并利用分子生物学来了解微进化对与出现相关的关键特征的影响。