Family-Based HIV Prevention for Latinos

描述（由申请人提供）：拉丁美洲人在被诊断患有艾滋病毒的人中所占比例不成比例，拉丁美洲青少年有可能参与可能导致艾滋病毒的性行为。然而，与其他族裔群体不同的拉丁裔青少年艾滋病毒预防干预措施的数据迄今尚未公布。这个K奖将专门为拉丁美洲家庭进行以家庭为基础的干预的初步研究。在NIMH少数民族补充奖的支持下，莱斯卡诺博士从非少数民族青年的多地点试验中改编了以家庭为基础的干预措施。莱斯卡诺博士采用定性方法，在干预措施中增加了与拉丁美洲人有关的家庭背景问题，如文化适应、宗教信仰、性别角色和性社会化、亲子沟通和监测做法。K奖的初始阶段将是三个队列（每组8个家庭）的适应性家庭干预的运行，以进一步评估参与者的反应和适当性。然后，将根据结构化离职面谈的反馈意见对干预措施进行修订。接下来，100个13至18岁青少年的拉丁美洲家庭将被随机分配到以家庭为基础的艾滋病毒预防干预或一般健康促进（GHP）条件，重点是健康行为，如饮食和锻炼。小组由6至8名家长和青少年组成，为期一天，7小时的工作坊。这两种干预措施分别为青年和家长开展活动（例如，重点关注青少年的脆弱性）以及父母和青少年的共同努力。该项目将通过评估青少年与艾滋病毒有关的性行为和态度、性别和性社会化、亲子沟通和父母监督的变化来估计拉丁美洲家庭为基础的艾滋病毒预防干预的效果。将在基线和干预后3个月和6个月完成测量。在这个K奖所做的工作将提供试点数据，这将导致提交R01，以确定干预措施的有效性，相比之下，只有一个以技能为基础的艾滋病毒预防组和一般健康促进组，在更大的样本拉丁美洲人。拉丁美洲社区迫切需要有效的干预。

DESCRIPTION (provided by applicant): Latinos are disproportionately represented among those diagnosed with HIV and Latino adolescents are at risk for engaging in sexual behaviors that can lead to HIV. However, data regarding HIV prevention interventions for Latino adolescents, as distinct from other ethnic groups, have not been published to date. This K Award will conduct an initial study of a family-based intervention specifically for Latino families. With the support of a NIMH Minority Supplement Award, Dr. Lescano has adapted a family-based intervention from a multi-site trial for non-minority youth. Using a qualitative approach, Dr. Lescano has added to the intervention family context issues relevant to Latinos such as acculturation, religiosity, gender role and sexual socialization, parent-child communication, and monitoring practices. The initial phase of the K Award will be a run-through of the adapted family-based intervention with three cohorts (8 families per group) to further assess participant reaction and appropriateness. The intervention will then be revised based on feedback using structured exit interviews. Next, 100 Latino families with an adolescent between the ages of 13 and 18 will be randomized into either the family based HIV prevention intervention or a general health promotion (GHP) condition that focuses on healthy behaviors such as diet and exercise. Groups consist of 6 to 8 parent and youth dyads in a one-day, 7-hour workshop. Both interventions employ activities for youth and parents separately (e.g., focus on adolescent vulnerability) and parents and adolescents together. The project will estimate the effect size of the Latino Family-based HIV prevention intervention from assessment of changes in the adolescents' HIV-related sexual behavior and attitudes, gender and sexual socialization, parent-child communication, and parental monitoring. Measures will be completed at baseline and at 3 and 6 months post-intervention. The work done in this K Award will provide pilot data that will lead to submission of an R01 to determine the efficacy of the intervention, compared to a adolescent-only, skills-based HIV prevention group and a general health promotion group, in a larger sample of Latinos. An efficacious intervention is urgently needed for Latino communities.