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Genetics of melanoma risk factors

Genetics of melanoma risk factors
黑色素瘤危险因素的遗传学
批准号：
nhmrc : 241944
负责人：
Dr David Duffy
金额：
$44.46万
依托单位：
Queensland Institute of Medical Research
依托单位国家：
澳大利亚
项目类别：
NHMRC Project Grants
财政年份：
2003
资助国家：
澳大利亚
项目状态：
已结题
起止时间：
2003-01-01 至 2005-12-31
来源：
https://researchdata.edu.au/genetics-melanoma-risk-factors/101316
关键词：
Geneticsmelanomariskfactors

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中文摘要
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英文摘要
A large mole (melanocytic nevi) count is the strongest known risk factor for melanoma. An understanding of the factors governing naevus development may therefore lead to important insights into the etiology of melanoma. We shall carry out molecular genetic analysis of DNA samples collected from twins and their parents with the aim of identifying major genes affecting moliness, pigmentation and other risk factors for melanoma. The importance of this study is that it will significantly advance our understanding of the relationship between moliness and melanoma risk and may lead to new therapeutic interventions.
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会议论文
Genetics of complex traits in multiply phenotyped twin sibships: the Brisbane Longitudinal Twin Study
Genetic epidemiology of complex disease
Defining the mechanism of melanoma and naevus risk on chromosome 9p21
Elucidating genetic mechanisms responsible for familial hyperaldosteronism type II
  • 批准号：
    nhmrc : 631580
  • 项目类别：
    NHMRC Project Grants
  • 资助金额：
    $28.33万
  • 财政年份：
    2010
  • 负责人：
    Dr David Duffy
  • 依托单位：
    The University of Queensland
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