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Improved liver function and regeneration with A20

Improved liver function and regeneration with A20
A20 改善肝功能和再生
批准号：
7173743
负责人：
CHRISTIANE FERRAN
金额：
$34.09万
依托单位：
BETH ISRAEL DEACONESS MEDICAL CENTER
依托单位国家：
美国
项目类别：
财政年份：
2003
资助国家：
美国
项目状态：
已结题
起止时间：
2003-01-01 至 2008-05-31
来源：
https://reporter.nih.gov/project-details/7173743
关键词：
AdenovirusesAnimalsApoptosisApoptoticBCL2 geneBiochemicalBromodeoxyuridineCCAAT-Enhancer-Binding ProteinsCaspaseCell CycleCell LineCell NucleusCessation of lifeCyclin Regulation of Cell Cycle PathwayCyclin-Dependent KinasesDNA RepairEMSAExcisionFaceGene ExpressionGrowth FactorHepatectomyHepaticHepatocyteHourHumanImmunohistochemistryIn SituIn Situ Nick-End LabelingIn VitroInterleukin-6IschemiaLabelLiverLiver FailureMediatingMembrane PotentialsMolecularMorbidity - disease rateMusNatural regenerationNecrosisNorthern BlottingNumbersPCNA genePathologyPathway interactionsPhysiological reperfusionPolymerasePrincipal InvestigatorPrintingReactive Oxygen SpeciesReadingRecombinantsRecoveryReperfusion InjuryReperfusion TherapyResearch Project GrantsRiboseSTAT3 geneScreening procedureSeriesSignal TransductionStimulusStructureSurgical ModelsTNF geneTP53 geneTestingTransaminasesTranscription Factor AP-1Transcription factor genesWorkactinomycinbasec-myc Genescell typecytochrome ccytokinegene therapyimprovedin vivoliver cell proliferationliver functionliver transplantationmitochondrial membranemutantnovelnovel therapeuticsprogramsprotective effectprotein aminoacid sequenceresponsesuccesstherapeutic targettranscription factor

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