MOLECULAR ONTOGENY OF ORAL MUCOSAL RESISTANCE TO SIV
MOLECULAR ONTOGENY OF ORAL MUCOSAL RESISTANCE TO SIV
批准号:
7349715
负责人:
MICHAEL E SELSTED
金额:
$15.67万
依托单位国家:
美国
项目类别:
财政年份:
2006
资助国家:
美国
项目状态:
已结题
起止时间:
2006-05-01 至 2007-04-30
中文摘要
本子项目是利用由NIH/NCRR资助的中心赠款提供的资源的众多研究子项目之一。子项目和研究者(PI)可能已经从另一个NIH来源获得了主要资金,因此可以在其他CRISP条目中表示。列出的机构是中心的,不一定是研究者的机构。目的:(1)确定恒河猴口腔中与防御素(具有抗病毒活性的先天免疫肽)相关的抗SIV抗性的年龄依赖性差异;(2)确定外源性局部给予防御素是否可以改变新生恒河猴对口腔SIV感染的易感性。
英文摘要
This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Objective: (1) identify age-dependent differences in anti-SIV resistance associated with defensins, innate immune peptides with antiviral activity, in the oral cavity of rhesus macaques and, (2) determine whether exogenous, topically administered defensins can alter the susceptibility of neonatal rhesus macaques to oral SIV infection.
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会议论文
Regulation of Mucosal Immunity by Pro- and Anti-inflammatory Salivary Defensins
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批准号:8665891
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项目类别:
-
资助金额:$38.89万
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财政年份:2010
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负责人:MICHAEL E SELSTED
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依托单位:
Regulation of Mucosal Immunity by Pro- and Anti-inflammatory Salivary Defensins
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批准号:8127613
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项目类别:
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资助金额:$38.11万
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财政年份:2010
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负责人:MICHAEL E SELSTED
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依托单位:
Regulation of Mucosal Immunity by Pro- and Anti-inflammatory Salivary Defensins
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批准号:8269132
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项目类别:
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资助金额:$38.89万
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财政年份:2010
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负责人:MICHAEL E SELSTED
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依托单位:
Regulation of Mucosal Immunity by Pro- and Anti-inflammatory Salivary Defensins
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批准号:8462591
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项目类别:
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资助金额:$37.34万
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财政年份:2010
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负责人:MICHAEL E SELSTED
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依托单位:
MOLECULAR ONTOGENY OF ORAL MUCOSAL RESISTANCE TO SIV
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批准号:7716117
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项目类别:
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资助金额:$30.68万
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财政年份:2008
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负责人:MICHAEL E SELSTED
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依托单位:
Physiologic Peptide Cyclization in Myeloid Cells
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批准号:7238738
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项目类别:
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资助金额:$36.15万
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财政年份:2004
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负责人:MICHAEL E SELSTED
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依托单位:
Physiologic Peptide Cyclization in Myeloid Cells
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批准号:7070049
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项目类别:
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资助金额:$37.23万
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财政年份:2004
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负责人:MICHAEL E SELSTED
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依托单位:
Physiologic Peptide Cyclization in Myeloid Cells
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批准号:6823638
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项目类别:
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资助金额:$37.88万
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财政年份:2004
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负责人:MICHAEL E SELSTED
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依托单位:
Physiologic Peptide Cyclization in Myeloid Cells
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批准号:7112585
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项目类别:
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资助金额:$2.64万
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财政年份:2004
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负责人:MICHAEL E SELSTED
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依托单位:
Physiologic Peptide Cyclization in Myeloid Cells
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批准号:7420995
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项目类别:
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资助金额:$35.46万
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财政年份:2004
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负责人:MICHAEL E SELSTED
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依托单位:
Physiologic Peptide Cyclization in Myeloid Cells
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批准号:6894641
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项目类别:
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资助金额:$38.1万
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财政年份:2004
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负责人:MICHAEL E SELSTED
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依托单位:
Molecular Ontogeny of Oral Mucosal Resistance to SIV
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批准号:6833954
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项目类别:
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资助金额:$51.96万
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财政年份:2003
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负责人:MICHAEL E SELSTED
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依托单位:
Molecular Ontogeny of Oral Mucosal Resistance to SIV
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批准号:6994462
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项目类别:
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资助金额:$55.97万
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财政年份:2003
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负责人:MICHAEL E SELSTED
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依托单位:
Molecular Ontogeny of Oral Mucosal Resistance to SIV
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批准号:7151221
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项目类别:
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资助金额:$57.33万
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财政年份:2003
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负责人:MICHAEL E SELSTED
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依托单位:
Molecular Ontogeny of Oral Mucosal Resistance to SIV
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批准号:6695544
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项目类别:
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资助金额:$45.41万
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财政年份:2003
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负责人:MICHAEL E SELSTED
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依托单位:
DRUG DISCOVERY FOR TREATMENT OF CRYPTOCOCCAL DISEASE
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批准号:3547861
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项目类别:
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资助金额:$81.91万
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财政年份:1991
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负责人:MICHAEL E SELSTED
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依托单位:
DRUG DISCOVERY FOR TREATMENT OF CRYPTOCCAL DISEASE
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批准号:3547859
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项目类别:
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资助金额:$78.9万
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财政年份:1991
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负责人:MICHAEL E SELSTED
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依托单位:
DRUG DISCOVERY FOR TREATMENT OF CRYPTOCOCCAL DISEASE
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批准号:2066666
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项目类别:
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资助金额:$68.44万
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财政年份:1991
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负责人:MICHAEL E SELSTED
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依托单位:
DRUG DISCOVERY FOR TREATMENT OF CRYPTOCOCCAL DISEASE
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批准号:3547860
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项目类别:
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资助金额:$78.83万
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财政年份:1991
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负责人:MICHAEL E SELSTED
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依托单位:
MOLECULAR ASPECTS OF LEUKOCYTE ANTIMICROBIAL PEPTIDES
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批准号:6510343
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项目类别:
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资助金额:$37.6万
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财政年份:1989
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负责人:MICHAEL E SELSTED
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依托单位:
海外基金