ORIGINS OF FIBRE CRIMP FROM PROTEIN TYPE & STRUCTURE

蛋白质类型纤维卷曲的起源

• 批准号: 7358023
• 负责人: JONATHAN CALDWELL
• 金额: $ 1.22万
• 依托单位: UNIVERSITY OF CALIFORNIA, SAN DIEGO
• 依托单位国家: 美国
• 财政年份: 2006
• 资助国家: 美国
• 起止时间: 2006-05-01 至 2007-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7358023
• 关键词: ORIGINS; FIBRE; CRIMP; PROTEIN; TYPE

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The goal of this project is to determine the 3-D arrangement of intermediate filaments in the three cortical cell types (ortho-, meso-, and paracortex) in longitudinally sectioned wool fibres. Previous work conducted at the Bio3-D lab in Boulder, Colorado focussed on transversely sectioned wool fibres. It is expected that more long-range information regarding the arrangements of the intermediate filaments will be obtained with longitudinally sectioned wool fibres. The arrangements of these intermediate filaments within each of three different cortical cells plays an important role in the overall curvature or crimp of the wool fibre.

这个子项目是利用由NIH/NCRR资助的中心拨款提供的资源的许多研究子项目之一。子项目和调查员(PI)可能从另一个NIH来源获得了主要资金，因此可能会出现在其他CRISE条目中。列出的机构是针对中心的，而不一定是针对调查员的机构。本项目的目标是确定纵向切割的羊毛纤维中三种皮质细胞类型(正皮层、中皮层和副皮质)中中间细丝的三维排列。之前在科罗拉多州博尔德的Bio3-D实验室进行的工作主要集中在横截面的羊毛纤维上。可以预期的是，从纵向切割的羊毛纤维中可以获得更多关于中间长丝排列的远程信息。这些中间细丝在三个不同的皮质细胞中的排列对羊毛纤维的整体弯曲或卷曲起着重要的作用。