DEFINING REGULATORS OF RNA POLYMERASE I FUNCTION IN S CEREVISIAE

定义酿酒酵母中 RNA 聚合酶 I 功能的调节因子

• 批准号: 7420695
• 负责人: Masayasu Nomura
• 金额: $ 0.29万
• 依托单位: UNIVERSITY OF WASHINGTON
• 依托单位国家: 美国
• 财政年份: 2006
• 资助国家: 美国
• 起止时间: 2006-09-20 至 2007-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7420695
• 关键词: DNA directed RNA polymerase; antibiotics; emotions; mass spectrometry; starvation

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. We are using mass spectrometry combined with in vitro activity assays to identify specific factors or modifications that affect Pol I activity in response to a variety of treatments (amino acid starvation, antibiotics,

该子项目是利用NIH/NCRR资助的中心赠款提供的资源的许多研究子项目之一。子项目和研究者（PI）可能从另一个NIH来源获得了主要资金，因此可以在其他CRISP条目中表示。所列机构为中心机构，不一定为研究者机构。我们正在使用质谱结合体外活性测定来鉴定影响Pol I活性的特定因子或修饰，这些因子或修饰响应于各种治疗（氨基酸饥饿、抗生素、