SALIENCE OR GAIN? COMPARING ACCOUNTS OF NUCLEUS ACCUMBENS FUNCTION

突出还是增益？

• 批准号: 7358797
• 负责人: JEFFREY A COOPER
• 金额: $ 0.31万
• 依托单位: STANFORD UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2006
• 资助国家: 美国
• 起止时间: 2006-06-01 至 2007-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7358797
• 关键词: SALIENCE; GAIN; COMPARING; ACCOUNTS; NUCLEUS

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. According to distinct hypotheses about the role of the ventral striatum in incentive processing, nucleus accumbens activation represents either anticipated gain (Knutson et al., 2001; Schultz, 2004) or general salience (Berridge & Robinson, 1998; Zink et al., 2004). In order to compare these accounts, we scanned participants with event-related fMRI as they performed a modified monetary incentive delay (MID) task (Knutson et al., 2001). The MID task included gain, neutral, and loss outcomes, some of which were probabilistic and some of which were guaranteed. We also probed self-reported arousal and valence during anticipation as participants played the task.

该子项目是利用NIH/NCRR资助的中心赠款提供的资源的许多研究子项目之一。子项目和研究者（PI）可能从另一个NIH来源获得主要资金，因此可以在其他CRISP条目中表示。所列机构为中心，不一定是研究者所在机构。根据关于腹侧纹状体在激励处理中的作用的不同假设，丘脑核激活代表预期的增益（Knutson等人，2001; Schultz，2004）或一般显著性（Berridge &罗宾逊，1998; Zink等人，2004年）。为了比较这些账户，我们用事件相关的fMRI扫描参与者，因为他们执行了修改的货币激励延迟（MID）任务（Knutson等人，2001年）的报告。MID任务包括收益、中性和损失结果，其中一些是概率性的，另一些是有保证的。我们还探讨了自我报告的唤醒和效价在预期的参与者发挥的任务。