Harnessing the immune system to battle ovarian cancer: A novel approach using naturally occurring exosomes

利用免疫系统对抗卵巢癌：一种利用天然外泌体的新方法

• 批准号: nhmrc : GNT1162413
• 金额: $ 53.51万
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2019
• 资助国家: 澳大利亚
• 起止时间: 2019-01-01 至 无数据
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/harnessing-immune-battle-occurring-exosomes/1379228
• 关键词: Harnessing; immune; system; battle; ovarian

Ovarian cancer is the most deadly type of gynaecologic disease with more than 1500 new cases being diagnosed each year in Australia. The goal of this research is to enhance the activity of immune cells such that they can start recognising and attacking ovarian tumour cells. Using naturally occurring vesicles, we have developed an effective strategy to switch off genes that prevent immune cells from entering ovarian tumour. Ultimately, our findings could significantly enhance patient survival.

卵巢癌是最致命的妇科疾病，在澳大利亚每年有超过1500例新病例被诊断出来。这项研究的目的是增强免疫细胞的活性，使它们能够开始识别和攻击卵巢肿瘤细胞。利用天然存在的囊泡，我们已经开发出一种有效的策略来关闭阻止免疫细胞进入卵巢肿瘤的基因。最终，我们的研究结果可以显着提高患者的生存率。