DEVELOPMENT OF A GUINEA PIG BRAIN ATLAS

该子项目是利用NIH/NCRR资助的中心赠款提供的资源的许多研究子项目之一。子项目和研究者（PI）可能从另一个NIH来源获得了主要资金，因此可以在其他CRISP条目中表示。所列机构为中心机构，不一定是研究者机构。豚鼠是另一种动物模型，优先于其他模型用于各种应用。然而，豚鼠大脑的准确MR图谱是不可用的。以与我们的小鼠大脑研究类似的方式，我们已经开始使用750 MHz仪器对离体豚鼠大脑进行数据采集。这需要更大的射频线圈（由资源构建）以优化SNR，并修改标准鼠标成像协议。数据采集最近才开始。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The guinea pig is another animal model used preferentially to other models for a variety of applications. However an accurate MR atlas of the guinea pig brain is not available. In a similar fashion to our mouse brain studies, we have begun data acquisition on excised guinea pig brains using the 750MHz instrument. This requires larger rf coils (constructed by the Resource) for optimized SNR, and modifications to the standard mouse imaging protocols. Data acquisition has only recently begun.