Meaning-Centered Group Psychotherapy in Advanced Cancer

晚期癌症以意义为中心的团体心理治疗

基本信息

  • 批准号:
    7194768
  • 负责人:
  • 金额:
    $ 41.17万
  • 依托单位:
  • 依托单位国家:
    美国
  • 项目类别:
  • 财政年份:
    2007
  • 资助国家:
    美国
  • 起止时间:
    2007-01-01 至 2011-12-31
  • 项目状态:
    已结题

项目摘要

DESCRIPTION (provided by applicant): Spirituality and its role in end-of-life care has emerged as a central issue in palliative care. There have been several recent studies of terminally ill cancer and AIDS patients by our research group demonstrating the central role of spiritual well being, and "meaning" in particular, in buffering against depression, hopelessness, and desire for hastened death. We have developed, manualized and piloted an 8-week Meaning-Centered Group Psychotherapy, designed to help patients with advanced cancer sustain or enhance a sense of meaning, peace, purpose, spiritual well-being and hope as they approach the end-of-life. Preliminary findings, based on an R21 grant, suggest that our Meaning-Centered intervention significantly reduced psychological distress and desire of hastened death, and significantly increased spiritual well-being and sense of meaning and purpose in life in a sample of advanced cancer patients. This project's overall aim is to conduct a randomized controlled trial of the efficacy of this new and-unique spiritually-based psychotherapy intervention for advanced cancer patients in enhancing psychological and spiritual well-being and quality of life. Specifically, we will examine the efficacy of Meaning-Centered Group Psychotherapy, compared to a standardized Supportive Group Psychotherapy, in enhancing spiritual well being and quality of life, and reducing psychological distress (anxiety and depression) and end-of-life despair (conceptualized as hopelessness, desire for hastened death, and suicidal ideation). In additon, we will examine clinical and demographic variables that may mediate or moderate treatment response to Meaning-Centered Group Psychotherapy in this population. 320 patients with stage IV solid tumor cancers will be randomized to receive 1 of these 2 interventions(160 patients randomized to each arm, anticipating an attrition rate of 40% would thus leave 96 patients per arm who complete the entire trial). Subjects will be assessed with a battery of self-report measure at 3 points: baseline/pre-intervention, post-intervention, and at 2 months post-intervention follow-up. This study will provide essential efficacy data on a novel and innovative psychotherapy intervention for patients with advanced cancer, incorporating spiritual (meaning-centered) elements, which holds great promise in the treatment of spiritual suffering at the end-of-life.
描述(由申请人提供):灵性及其在临终关怀中的作用已成为姑息治疗的核心问题。我们的研究小组最近对癌症和艾滋病晚期患者进行了几项研究,证明了精神健康的核心作用,特别是“意义”,在缓冲抑郁,绝望和加速死亡的欲望方面。我们已经开发,手动化和试点为期8周的意义为中心的团体心理治疗,旨在帮助晚期癌症患者维持或增强意义感,和平,目的,精神健康和希望,因为他们接近生命的尽头。基于R21资助的初步研究结果表明,我们以意义为中心的干预措施显著减少了晚期癌症患者样本中的心理困扰和加速死亡的愿望,并显著增加了精神幸福感以及生活的意义和目的感。该项目的总体目标是进行一项随机对照试验,研究这种新的独特的以精神为基础的心理治疗干预对晚期癌症患者在提高心理和精神健康以及生活质量方面的疗效。具体来说,我们将研究意义中心团体心理治疗的有效性,与标准化的支持性团体心理治疗相比,在提高精神健康和生活质量,减少心理困扰(焦虑和抑郁)和临终绝望(概念化为绝望,渴望加速死亡和自杀意念)方面。此外,我们还将研究在这一人群中可能介导或调节意义中心团体心理治疗反应的临床和人口统计学变量。320例IV期实体瘤癌症患者将随机接受这2种干预措施之一(每组随机分配160例患者,预计损耗率为40%,因此每组96例患者完成整个试验)。将在3个时间点(基线/干预前、干预后和干预后2个月随访时)采用一组自我报告指标对受试者进行评估。这项研究将为晚期癌症患者提供一种新颖和创新的心理治疗干预措施的基本疗效数据,其中包括精神(以意义为中心)元素,这在治疗临终时的精神痛苦方面具有很大的希望。

项目成果

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William Breitbart其他文献

William Breitbart的其他文献

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{{ truncateString('William Breitbart', 18)}}的其他基金

Meaning-Centered Psychotherapy Training for Cancer Care Providers
癌症护理人员以意义为中心的心理治疗培训
  • 批准号:
    9129452
  • 财政年份:
    2015
  • 资助金额:
    $ 41.17万
  • 项目类别:
Meaning-Centered Psychotherapy Training for Cancer Care Providers
癌症护理人员以意义为中心的心理治疗培训
  • 批准号:
    8931198
  • 财政年份:
    2015
  • 资助金额:
    $ 41.17万
  • 项目类别:
Meaning-Centered Psychotherapy Training for Cancer Care Providers
癌症护理人员以意义为中心的心理治疗培训
  • 批准号:
    9753144
  • 财政年份:
    2015
  • 资助金额:
    $ 41.17万
  • 项目类别:
Meaning-Centered Psychotherapy Training Program for Cancer Care Clinicians
癌症护理临床医生以意义为中心的心理治疗培训计划
  • 批准号:
    10687062
  • 财政年份:
    2015
  • 资助金额:
    $ 41.17万
  • 项目类别:
Meaning-Centered Psychotherapy Training Program for Cancer Care Clinicians
癌症护理临床医生以意义为中心的心理治疗培训计划
  • 批准号:
    10460914
  • 财政年份:
    2015
  • 资助金额:
    $ 41.17万
  • 项目类别:
Individual Meaning-Centered Psychotherapy in Advanced Cancer Patients
晚期癌症患者以个体意义为中心的心理治疗
  • 批准号:
    8509614
  • 财政年份:
    2010
  • 资助金额:
    $ 41.17万
  • 项目类别:
Individual Meaning-Centered Psychotherapy in Advanced Cancer Patients
晚期癌症患者以个体意义为中心的心理治疗
  • 批准号:
    8874139
  • 财政年份:
    2010
  • 资助金额:
    $ 41.17万
  • 项目类别:
Individual Meaning-Centered Psychotherapy in Advanced Cancer Patients
晚期癌症患者以个体意义为中心的心理治疗
  • 批准号:
    8282640
  • 财政年份:
    2010
  • 资助金额:
    $ 41.17万
  • 项目类别:
Individual Meaning-Centered Psychotherapy in Advanced Cancer Patients
晚期癌症患者以个体意义为中心的心理治疗
  • 批准号:
    8118424
  • 财政年份:
    2010
  • 资助金额:
    $ 41.17万
  • 项目类别:
Individual Meaning-Centered Psychotherapy in Advanced Cancer Patients
晚期癌症患者以个体意义为中心的心理治疗
  • 批准号:
    8725598
  • 财政年份:
    2010
  • 资助金额:
    $ 41.17万
  • 项目类别:
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