PERIODONTAL INFLAMMATION IN TYPE 1 DIABETES

该子项目是利用NIH/NCRR资助的中心赠款提供的资源的许多研究子项目之一。子项目和研究者（PI）可能从另一个NIH来源获得了主要资金，因此可以在其他CRISP条目中表示。所列机构为中心机构，不一定是研究者机构。众所周知，1型糖尿病患者比非糖尿病人群表现出更高的牙周病发病率和严重程度。总的来说，糖尿病患者感染的发生率增加，并且糖尿病患者的感染最有可能具有复杂的病程。本研究的目的是探讨中性粒细胞对牙龈卟啉单胞菌和牙龈炎的反应在I型糖尿病患者牙周病。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. It is well established that type 1 diabetics exhibit a greater incidence and severity of periodontal disease that non diabetic populations. Overall, the incidence of infection is increased in patients with diabetes mellitus and infections are most likely to have a complicated course in diabetics that in non diabetic. The objective of this study is to examine the neutrophil response to P. gingivitis and gingivitis in Type I diabetes patients with periodontal disease.