BUPROPION VS PLACEBO IN THE TREATMENT OF PATHOLOGICAL GAMBLING

安非他酮与安慰剂治疗病理性赌博的比较

• 批准号: 7377008
• 负责人: DONALD W. BLACK
• 金额: $ 0.33万
• 依托单位: UNIVERSITY OF IOWA
• 依托单位国家: 美国
• 财政年份: 2006
• 资助国家: 美国
• 起止时间: 2006-03-01 至 2007-02-28
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7377008
• 关键词: BUPROPION; VS; PLACEBO; TREATMENT; PATHOLOGICAL

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Pathological gambling (PG) has become a major health concern, particularly as gambling opportunities have proliferated. Despite its importance, there are few treatment options with proven efficacy. The goal of this project is to conduct a randomized, double-blind comparison of bupropion-SR versus placebo in the treatment of PG. Bupropion will be used because of its reported efficacy in treating attention-deficit hyperactivity disorder (ADHD), and clinical similarities between PG and ADHD. This study will be one of the first of its kind, and has the potential to provide pilot data supporting the efficacy of a novel treatment for PG.

该子项目是利用NIH/NCRR资助的中心赠款提供的资源的许多研究子项目之一。子项目和研究者（PI）可能从另一个NIH来源获得主要资金，因此可以在其他CRISP条目中表示。所列机构为中心，不一定是研究者所在机构。病态赌博（PG）已成为一个主要的健康问题，特别是随着赌博机会的激增。尽管其重要性，但很少有经证实有效的治疗方案。本项目的目的是进行一项随机、双盲比较安非他酮缓释剂与安慰剂治疗PG。安非他酮将被使用，因为它在治疗注意力缺陷多动障碍（ADHD）的疗效报告，和PG和ADHD之间的临床相似性。这项研究将是同类研究中的第一项，并有可能提供支持PG新型治疗疗效的初步数据。