IOWA COCHLEAR IMPLANT PROJECT

该子项目是利用NIH/NCRR资助的中心赠款提供的资源的许多研究子项目之一。子项目和研究者（PI）可能从另一个NIH来源获得主要资金，因此可以在其他CRISP条目中表示。所列机构为中心，不一定是研究者所在机构。爱荷华州人工耳蜗植入项目多年来一直从事儿童和成人人工耳蜗植入的临床结局研究。多年来，人工耳蜗植入体的言语感知已经得到改善，以至于植入考虑的选择标准定义不清。因此，当前研究的重点是完善人工耳蜗植入的标准。本研究的总体目标是：1）研究扩大植入的选择标准，以包括听力更好的成年人和早期植入儿童; 2）制定可靠的评估策略，包括准确评估听觉阈值，以确定儿童是否适合在12个月大时植入人工耳蜗; 3）开发和评估用于语音感知和音乐欣赏的新型信号处理; 4）使用新设计的短电极植入物评估具有更多残余听力的成年人的电信号处理和声放大的组合; 5）改进和扩大电生理测量的使用，以改善现有的和高速率的语音处理器对幼儿和成人的适应性; 6）评估沟通结果（言语产生、语言、阅读、写作、（音乐欣赏）使用助听器的听力受损儿童和植入物的儿童，以确定是否应将植入物选择标准扩展到包括儿童更多的听力; 7）研究双耳人工耳蜗植入的益处; 8）确定影响儿童和成人人工耳蜗植入的长期益处的因素; 9）检查心理物理、心理、言语感知测量和感知准确性之间的关系，以及复杂音乐听音任务中的评价;（10）研究系统音乐训练与长期人工耳蜗植入对音乐感知和评价的影响; 11）评估语前和语后耳聋对音乐感知和评价的影响。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The Iowa Cochlear Implant program has been engaged in clinical outcomes research studying cochlear implants in children and adults for many years. Speech perception with cochlear implants has improved over the years to the point where selection criteria for implant consideration is poorly defined. The focus of the current study, therefore, is to refine the criteria for cochlear implantation. The overall goals of this research are to: 1) study expansion of selection criteria for implantation to include adults with more hearing and earlier implantation in children; 2) develop a reliable evaluation strategy including accurate assessment of auditory thresholds to determine if a child is a candidate for a cochlear implant by 12 months of age; 3) develop and evaluate novel signal processing for speech perception and music appreciation; 4) evaluate the combination of electrical signal processing and acoustical amplification in adults with more residual hearing using a newly designed short electrode implant; 5) refine and expand the use of electrophysiologic measures to improve fitting of existing and high rate speech processors for young children and adults; 6) assess the communication outcomes (speech production, language, reading, writing, and music appreciation) of children with hearing impairment using hearing aids and those with implants to determine if implant selection criteria should be expanded to include children with more hearing; 7) study the benefits of binaural cochlear implants; 8) determine the factors that affect the long-term benefit of cochlear implants in children and adults; 9) examine the relations among psychophysical, psychological, speech perception measures, and perceptual accuracy, and appraisal in complex music listening tasks; 10) to examine the impact of systematic music training versus long term cochlear implant use on music perception and appraisal; and 11) assess the impact of prelingual versus postlingual onset of deafness on music perception and appraisal.