PHASE III RANDOMIZED CROSS-OVER STUDY USING NEBULIZED FENTANYL FOR DYSPNEA

使用芬太尼雾化治疗呼吸困难的 III 期随机交叉研究

• 批准号: 7375149
• 负责人: THOMAS JAMES. SMITH
• 金额: $ 0.06万
• 依托单位: VIRGINIA COMMONWEALTH UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2005
• 资助国家: 美国
• 起止时间: 2005-12-01 至 2006-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7375149
• 关键词: PHASE; III; RANDOMIZED; CROSS; OVER

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The purpose of this study is to establish that inhaled, or nebulized fentanyl is an effective treatment for cancer related dyspnea, resulting in improved breathing, Fentenyl is an opioid analgesic, often used for pain relief. Previous studies indicate that similar medications such as morphine may be effective in relieving cancer-related shortness of breath. The specific aim is to determine if nebulized fentanyl relieves dyspnea in cancer patients compared to placebo.

该子项目是利用NIH/NCRR资助的中心赠款提供的资源的许多研究子项目之一。子项目和研究者（PI）可能从另一个NIH来源获得主要资金，因此可以在其他CRISP条目中表示。所列机构为中心，不一定是研究者所在机构。本研究的目的是确定吸入或雾化芬太尼是治疗癌症相关呼吸困难的有效方法，可改善呼吸，芬太尼是一种阿片类镇痛药，常用于缓解疼痛。以前的研究表明，类似的药物，如吗啡，可能有效地缓解癌症相关的呼吸急促。具体目的是确定与安慰剂相比，雾化芬太尼是否缓解癌症患者的呼吸困难。