DIABETES THERAPY IN CF PATIENTS WITH ABNORMAL GLUCOSE TOLERANCE

糖耐量异常的 CF 患者的糖尿病治疗

• 批准号: 7375192
• 负责人: RICHARD Barry MOSS
• 金额: $ 0.13万
• 依托单位: STANFORD UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2005
• 资助国家: 美国
• 起止时间: 2005-12-01 至 2006-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7375192
• 关键词: DIABETES; THERAPY; CF; PATIENTS; ABNORMAL

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Currently Cystic Fibrosis (CF) patients with impaired insulin secretion are not routinely treated with exogenous insulin if their fasting glucose levels are normal. This study aims to show that chronic treatment with either insulin or an oral stimulator of endogenous insulin secretion will lead to improved muscle mass and clinical status in insulin-deficient adults with CF.

本子项目是利用由NIH/NCRR资助的中心赠款提供的资源的众多研究子项目之一。子项目和研究者（PI）可能已经从另一个NIH来源获得了主要资金，因此可以在其他CRISP条目中表示。列出的机构是中心的，不一定是研究者的机构。目前，如果空腹血糖水平正常，胰岛素分泌受损的囊性纤维化（CF）患者不常规使用外源性胰岛素治疗。本研究旨在表明，慢性胰岛素治疗或口服内源性胰岛素分泌刺激剂将改善患有CF的胰岛素缺乏成人的肌肉质量和临床状况。