P3 RAN DB -LETROZOLE VS PLAC PRIMARY BR CA COMPLETING 5 OR 5+ YRS OF ADJ TAMOXIF

该子项目是利用NIH/NCRR资助的中心赠款提供的资源的许多研究子项目之一。子项目和研究者（PI）可能从另一个NIH来源获得主要资金，因此可以在其他CRISP条目中表示。所列机构为中心，不一定是研究者所在机构。初步研究表明，如果在服用他莫昔芬五年后服用来曲唑，癌症复发可能会减少。本研究的目的是找出是否接受来曲唑或停止他莫昔芬后，没有进一步的治疗更好。第二个目的是确定治疗如何影响生活质量。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Preliminary research suggests cancer recurring may be reduced if letrozole is taken after five years of tamoxifen. The purpose of this study is to find out whether it is better to receive letrozole or no further treatment after stopping tamoxifen. The second purpose is to determine how the treatment affects the quality of life.