PRETERM SKIN CONTACT EFFECTS OF ELECTROPHYSIOLOGIC SLEEP

该子项目是利用NIH/NCRR资助的中心赠款提供的资源的许多研究子项目之一。子项目和研究者（PI）可能从另一个NIH来源获得主要资金，因此可以在其他CRISP条目中表示。所列机构为中心，不一定是研究者所在机构。母研究“早产儿皮肤接触对电生理睡眠的影响”的目的是确定母亲和早产儿之间的皮肤接触（SSC）对基于电生理的睡眠的影响，方法是对32-41周的受孕后年龄（PCA）住院早产儿进行随机对照临床试验，以测试与改善SSC组睡眠相关的几个假设和研究问题。研究参与者将被分为两组-60名对照受试者将在预试验和试验期间留在培养箱中，60名SSC受试者将在预试验期间留在培养箱中，并在试验期间接受SSC。睡眠技术人员将连接电极并收集EEG数据约6小时。本方案最初于2002年4月10日获得IRB批准，并一直在招募受试者。研究者现在利用GCRC空间在40周时进行1次门诊访视，以收集仅10例受试者的纵向EEG数据。收集10名受试者的初步数据是为了查看在该时间点是否存在任何可测量的差异。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The purpose of the parent study "Preterm Skin Contact Effects on Electrophysiologic Sleep" is to determine the effect of skin-to-skin contact (SSC) between mother and preterm infant on electrophysiologic-based sleep by conducting a randomized controlled clinical trial with 32-41 weeks postconception age (PCA) hospitalized premature infants to test several hypotheses and research questions related to improved sleep in the SSC group. The study participants will be divided into two groups-60 control subjects will stay in the incubator throughout the pretest and test periods and 60 SSC subjects will be in the incubator during pretest and receive SSC during the test period. A sleep technician will attach electrodes and collect EEG data for about 6 hours. This protocol was originally IRB-approved on 4/10/02 and has been accruing subjects. The investigator now utilizes GCRC space to conduct 1 outpatient visit at 40 weeks to collect longitudinal EEG data on just 10 subjects. The collection of pilot data on 10 subjects is to see if there are any measurable differences at that time point.