FAT DISTRIBUTION IN CHILDREN OF NORMAL WOMEN AND WOMEN WITH GESTATIONAL DIABETES

这个子项目是利用由NIH/NCRR资助的中心拨款提供的资源的许多研究子项目之一。子项目和调查员(PI)可能从另一个NIH来源获得了主要资金，因此可能会出现在其他CRISE条目中。列出的机构是针对中心的，而不一定是针对调查员的机构。这项提案将确定与正常糖耐量(NGT)和妊娠期糖尿病(GDM)妇女的后代的儿童肥胖和相关后遗症有关的母亲和围产期因素。糖耐量正常和妊娠期糖尿病妇女的婴儿的身体成分的纵向变化将在1岁和6-10岁时进行评估。这些6-10岁儿童的葡萄糖耐量将通过葡萄糖耐量试验进行评估。获得的其他测试包括血脂谱、DEXA的身体成分和遗传分析。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. This proposal will determine the maternal and perinatal factors related to childhood obesity and related sequela in the offspring of women with normal glucose tolerance (NGT) and gestational diabetes mellitus (GDM). Longitudinal changes in body composition in infants of women with normal glucose tolerance and gestational diabetes will be evaluated at 1 year and at ages 6-10. Glucose tolerance will be evaluated in these children, age 6-10 years, using a glucose tolerance test. Additional tests obtained include a lipid profile, body composition by DEXA and genetic analysis.