FAT DISTRIBUTION IN CHILDREN OF NORMAL WOMEN AND WOMEN WITH GESTATIONAL DIABETES

该子项目是利用NIH/NCRR资助的中心赠款提供的资源的许多研究子项目之一。子项目和研究者（PI）可能从另一个NIH来源获得主要资金，因此可以在其他CRISP条目中表示。所列机构为中心，不一定是研究者所在机构。这项建议将确定母亲和围产期因素与儿童肥胖和相关后遗症的妇女与正常葡萄糖耐量（NGT）和妊娠期糖尿病（GDM）的后代。将在1岁和6-10岁时评估糖耐量正常和妊娠糖尿病妇女的婴儿身体组成的纵向变化。 将使用葡萄糖耐量试验评价这些6-10岁儿童的葡萄糖耐量。获得的其他测试包括血脂谱，DEXA身体成分和遗传分析。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. This proposal will determine the maternal and perinatal factors related to childhood obesity and related sequela in the offspring of women with normal glucose tolerance (NGT) and gestational diabetes mellitus (GDM). Longitudinal changes in body composition in infants of women with normal glucose tolerance and gestational diabetes will be evaluated at 1 year and at ages 6-10. Glucose tolerance will be evaluated in these children, age 6-10 years, using a glucose tolerance test. Additional tests obtained include a lipid profile, body composition by DEXA and genetic analysis.