CYP2B6 POLYMORPHISMS: NEVIRAPINE/EFAVIRENZ METABOLISM

CYP2B6 多态性：奈韦拉平/依非韦伦代谢

• 批准号: 7375642
• 负责人: grant R. wilkinson
• 金额: $ 32.13万
• 依托单位: VANDERBILT UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2005
• 资助国家: 美国
• 起止时间: 2005-12-01 至 2006-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7375642
• 关键词: CYP2B6; POLYMORPHISMS; NEVIRAPINE; EFAVIRENZ; METABOLISM

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Hypothesis: Interindividual and population differences in drug metabolism and dispotion of efavirenz and nevirapine are a consequence of genetic variability in CYP2B6

这个子项目是利用由NIH/NCRR资助的中心拨款提供的资源的许多研究子项目之一。子项目和调查员(PI)可能从另一个NIH来源获得了主要资金，因此可能会出现在其他CRISE条目中。列出的机构是针对中心的，而不一定是针对调查员的机构。假说：药物代谢和药物分配的个体间和群体间差异是CYP2B6基因变异的结果