HUMAN T CELL RESPONSES TO RSV

人类 T 细胞对 RSV 的反应

• 批准号: 7375681
• 负责人: James E Crowe
• 金额: $ 1.3万
• 依托单位: VANDERBILT UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2005
• 资助国家: 美国
• 起止时间: 2005-12-01 至 2006-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7375681
• 关键词: HUMAN; CELL; RESPONSES; RSV

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The purpose of this research is to test the hypothesis that RSV-specific CD8+ T cells are the principal mechanism of resolution of infection and protection against reinfection during the first months of life, when passive maternal antibodies profoundly suppress humoral RSV-specific immunity.

该子项目是利用NIH/NCRR资助的中心赠款提供的资源的许多研究子项目之一。子项目和研究者（PI）可能从另一个NIH来源获得主要资金，因此可以在其他CRISP条目中表示。所列机构为中心，不一定是研究者所在机构。本研究的目的是检验RSV特异性CD 8 + T细胞是在生命最初几个月内解决感染和防止再感染的主要机制的假设，此时被动母体抗体深刻地抑制了RSV特异性体液免疫。