CALORIC RESTRICTION, OXIDATIVE DAMAGE AND LONGEVITY

热量限制、氧化损伤和长寿

• 批准号: 7375594
• 负责人: L Jackson Roberts, II
• 金额: $ 7.51万
• 依托单位: VANDERBILT UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2005
• 资助国家: 美国
• 起止时间: 2005-12-01 至 2006-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7375594
• 关键词: CALORIC; RESTRICTION; OXIDATIVE; DAMAGE; LONGEVITY

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Hypothesis: A low energy (calorie) diet will cause a decrease in oxidative stress assessed by measuring levels of F2-isoprostanes in healthy adults. Specific aim: Determine if placing individuals on a low energy (calorie) diet leads to a reduction in oxidative stress.

该子项目是利用NIH/NCRR资助的中心赠款提供的资源的许多研究子项目之一。子项目和研究者（PI）可能从另一个NIH来源获得主要资金，因此可以在其他CRISP条目中表示。所列机构为中心，不一定是研究者所在机构。假设：低能量（卡路里）饮食将导致通过测量健康成人中F2-异前列烷水平评估的氧化应激降低。具体目标：确定将个体置于低能量（卡路里）饮食是否会导致氧化应激减少。