AN INTERNATIONAL, MULTICENTER, RANDOMIZED, OPEN-LABEL, PARALLEL EFFICACY AND

该子项目是利用NIH/NCRR资助的中心赠款提供的资源的许多研究子项目之一。子项目和研究者（PI）可能从另一个NIH来源获得主要资金，因此可以在其他CRISP条目中表示。所列机构为中心，不一定是研究者所在机构。评估与帕米膦酸盐治疗患者相比，唑来膦酸治疗的重度骨质疏松症患者第12个月腰椎骨密度相对于基线的百分比变化。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. To assess the percentage change in lumbar spine bone mineral density at month 12 relative to baseline in zoledronic acid treated patients with severe oseogenisis imperfecta compared to pamidronate treated patients.