SYNTHESIS OF NITROALCOHOLS VIA HETEROGENEOUS CATALYSIS

这个子项目是利用由NIH/NCRR资助的中心拨款提供的资源的许多研究子项目之一。子项目和调查员(PI)可能从另一个NIH来源获得了主要资金，因此可能会出现在其他CRISE条目中。列出的机构是针对中心的，而不一定是针对调查员的机构。这项工作将研究更有效的合成硝化醇的方法，这些硝化醇作为生产所提议的四酯大环的前体。许多文献报道的上述醇的生成方法得到的不纯产物的产率都很低。该实验室希望扩大他们在硅胶介导的合成方面的工作。他们希望改变氨基硅烷化合物的特性，或许还能创造出新型聚合物，在硝化醇的形成过程中用作可回收的催化剂。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. This work will examine more efficient methods for the synthesis of nitroalcohols, which serve as precursors for the production of the proposed tetraester macrocycle. Many of the literature methods for the creation of the above alcohols give low yields of impure products. The lab wishes to expand their work of silica gel mediated synthesis. They hope to change the characteristics of aninosilane compounds and perhaps create novel polymers that could serve as recyclable catalysts in the formation of nitroalcohols.