Harvard Planning Grant for Institutional Clinical and Translational Science Award

哈佛机构临床和转化科学规划拨款

• 批准号: 7215029
• 负责人: DANIEL EDWIN SINGER
• 金额: $ 25.43万
• 依托单位: HARVARD MEDICAL SCHOOL
• 依托单位国家: 美国
• 财政年份: 2006
• 资助国家: 美国
• 起止时间: 2006-09-17 至 2007-09-16
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7215029
• 关键词: NIH Roadmap Initiative tag; administrative personnel; biomedical facility; biomedical resource; career; clinical research; education evaluation /planning; health science research analysis /evaluation; health services research tag; information dissemination; medical education; training

DESCRIPTION (provided by applicant): We are submitting an application for a Planning Grant for an Institutional Clinical and Translational Science Award (CTSA) from the Harvard Medical School (HMS) and Harvard-affiliated Academic Health Centers (AHCs). Harvard is committed to establishing an academic home for clinical research, the Harvard Clinical and Translational Science Center (CISC), that will integrate resources across Harvard, facilitate productive interdisciplinary collaborations, foster successful career development through Roadmap T32 and K12Programs, link investigators with experts in potentially transformative technologies, such as genomics, advanced imaging, and bioengineering, provide pilot grant support for promising, interdisciplinary research, and generally speed translation of scientific insights into beneficial clinical care. In this proposal we describe our vision for the CISC, and a planning process to establish its governance, administration, content, and evaluation. Harvard's research resources, faculty, and trainees are extraordinary but frequently dispersed and isolated. Our CTSC will seek to integrate clinical research across Harvard to add new dimensions of research productivity benefiting patients. In the process we will integrate and realign our four separate General Clinical Research Centers. Informatics will reinforce the CTSC's links across disciplines and institutions. The magnitude of this task dictates that we start with a planning grant. We have constituted an Executive Committee composed of Harvard's leaders in clinical research and outlined subcommittees to address each of the critical components of the program. We will assemble an inventory of relevant resources and seek expert advice from within and outside Harvard. An organizational consultant will help us identify programmatic synergies and obstacles and help assure the planning process meets its milestones. The Principal Investigator is both an accomplished clinical investigator and an Associate Dean with a long history of success working across Harvard's institutional boundaries. The Trustees include the AHC CEOs and Chief Academic Officers as well as HMS Deans. These Trustees reflect broad institutional commitment to the Program and the authority to direct institutional change and investments of space and money to underwrite the Program. We believe our planning process is specific, innovative yet disciplined, and should be robust. A full and competitive CTSA application will be produced in a timely manner.

描述（由申请人提供）：我们正在提交一份申请，申请哈佛医学院（HMS）和哈佛附属学术健康中心（AHCs）的机构临床和转化科学奖（CTSA）的规划补助金。哈佛致力于建立一个临床研究的学术之家，即哈佛临床和转化科学中心（CISC），该中心将整合哈佛的资源，促进富有成效的跨学科合作，通过路线图T32和K12计划促进成功的职业发展，将研究人员与潜在变革技术（如基因组学，先进成像和生物工程）的专家联系起来，为有前途的跨学科研究提供试点赠款支持，并通常加速将科学见解转化为有益的临床护理。在本提案中，我们描述了我们对CISC的愿景，以及建立其治理、管理、内容和评估的规划流程。哈佛的研究资源、教师和实习生都是非凡的，但往往分散和孤立。我们的CTSC将寻求整合整个哈佛的临床研究，以增加有利于患者的研究生产力的新维度。在这个过程中，我们将整合和重新调整我们的四个独立的综合临床研究中心。信息学将加强CTSC跨学科和机构的联系。这项任务的重要性决定了我们必须从规划拨款开始。我们已经成立了一个执行委员会，由哈佛临床研究的领导人组成，并概述了小组委员会，以解决该计划的每个关键组成部分。我们将收集相关资源清单，并寻求哈佛内外的专家建议。一名组织顾问将帮助我们确定方案的协同作用和障碍，并帮助确保规划进程达到其里程碑。主要研究者既是一位有成就的临床研究者，也是一位副院长，在哈佛的机构边界上有着悠久的成功历史。受托人包括AHC首席执行官和首席学术官以及HMS院长。这些受托人反映了对该计划的广泛的机构承诺，以及指导机构变革和空间投资的权力和资金，以支持该计划。我们相信我们的规划过程是具体的，创新的，但纪律，应该是强大的。将及时提出一份全面和有竞争力的CTSA申请。