Wireless Subdural Electrode Array

描述（由申请人提供）：在这个转化SBIR项目中，我们将开发一种完全可植入的无线硬膜下电极网格，用于短期皮质脑电图监测（少于30天）。该设备将基于新颖的制造工艺，这将使无线植入物的合成与集成电子产品在低成本和价格上与现有的有线电网竞争。这种完全植入的硬脑膜下网格的可用性将大大降低住院费用和与皮质脑电图监测程序相关的感染率。公共卫生相关性：手术干预是一种昂贵、耗时且未充分利用的治疗癫痫的技术，只有不到5%的潜在辅助患者以这种方式接受治疗。完全植入的无线设备将降低感染率，对护理环境的要求也不那么严格，而更便宜的设备和护理方法将有助于降低医疗成本，增加潜在的治疗人群。这将使临床医生能够使用较便宜的治疗方案，并将癫痫监测程序从昂贵的神经内科重症监护病房移出。

DESCRIPTION (provided by applicant): In this translational SBIR program, we will develop a totally implantable, wireless, subdural electrode grid for short-term cortical EEG monitoring (less than 30 days). This device will be based upon novel manufacturing processes that will allow synthesis of the wireless implants with integrated electronics at low cost and prices that are competitive with existing wired grids. The availability of this fully implanted subdural grid will substantially reduce hospitalization costs and infection rates associated with cortical EEG monitoring procedures. PUBILC HEALTH RELEVANCE: Surgical intervention is an expensive, time intensive, underutilized technique to treat epilepsy, with less than 5% of the potentially aided patient population being treated in this way. A fully implanted wireless device will reduce infection rates and require a less stringent care environment, while cheaper devices and care methods will help to reduce health care costs and increase potential treatment populations. This will enable clinicians to use less expensive treatment options and to move epilepsy monitoring procedures out of expensive Neurology Intensive Care Units.