Clinical Resource Core

核心C：临床资源核心 该核心将集中招募系统性红斑狼疮受试者，不完全 红斑狼疮和健康对照用于本中心的研究翻译。专用 工作人员将负责受试者入组CORT的所有方面，包括遵守 人类受试者保护条例。临床中心将管理标准化的临床和 流行病学调查问卷，并获得受试者的病史和实验室信息。的 Core将处理用于这些研究的血液样本，并将储存DNA、RNA、血清和血浆。 临床核心的具体目标是： 1.招募系统性红斑狼疮、不完全性狼疮综合征、 健康的对照。 2.收集人口统计学、临床和流行病学数据，并将其存储在安全、 机密数据库。 3.收集和储存DNARNA、血浆和血清，以分发给研究人员， 科特 这些活动将作为现有的达拉斯地区自身免疫疾病登记处的一部分， 以充分利用现有的基础设施。通过将这些服务作为核心提供， 与受试者的互动将更有效、更经济，并有更好的质量控制。

CORE C: Clinical Resources Core This core will provide centralized recruitment of subjects with systemic lupus erythematosus, incomplete lupus erythematosus, and healthy controls for use in this Center of Research Translation. Dedicated personnel will be responsible for all aspects of subject enrollment into this CORT, including compliance with human subjects protection regulations. The Clinical Core will administer standardized clinical and epidemiological questionnaires and obtain the subject's medical history and laboratory information. The Core will process blood samples for use in these studies and will store DNA, RNA, serum, and plasma. The Specific Aims of the Clinical Core are: 1. Recruitment of subjects with systemic lupus erythematosus, incomplete lupus syndromes, and healthy controls. 2. Collection of demographic, clinical, and epidemiological data with storage in a secure, confidential database. 3. Collection and storage of DNARNA, plasma, and serum for distribution to researchers in the CORT These activities will be carried out as part of the existing Dallas Regional Autoimmune Disease Registry in order to leverage the infrastructure that is already in place. By providing these services as a Core, the interaction with subjects will be more effective and economical, with greater quality control.