GERMPLASM & PHYTOCHEMICAL PROFILING/NIKOLAU, BASIL
种质质
基本信息
- 批准号:7293904
- 负责人:
- 金额:$ 24.77万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2007
- 资助国家:美国
- 起止时间:2007-04-01 至 2010-03-31
- 项目状态:已结题
- 来源:
- 关键词:BiochemicalBiochemical GeneticsBotanicalsCharacteristicsChemicalsClinical TrialsCollectionCommunitiesConditionControlled EnvironmentCuesDataData CollectionDatabasesDevelopmentEchinacea (Asteraceae)Echinacea PreparationEnvironmentFingerprintHealth BenefitHumanHypericumInformation NetworksInformation ResourcesInternetIowaLaboratory ResearchLeadMedicinal PlantsMethodsOcimum basilicumPhytochemicalPlantsPopulationProductionPrunella (angiosperm)RangeRecommendationResearchResearch PersonnelResearch Project GrantsRiskRoleSeedsSorting - Cell MovementSourceSupport of ResearchSurveysSystemUniversitiesVariantdesigndietary supplementsimprovedmetabolomicsplant growth/developmenttool
项目摘要
Core A of the Iowa Center for Botanical Supplement Research has five long-term objectives in support of the
research being conducted within the Center to improve our understanding of the human health benefits and
potential risks of the dietary supplements, Echinacea, Hypericum, and Prunella.
First, we will expand comprehensive plant germplasm collections of Echinacea and Hypericum, and develop
collections of Prunella, in a manner designed to represent a broad range of taxonomic,genetic and
biochemical diversity, and to propagate the plants through control-pollinated seed production and vegetative
means. In this way, these well-documented and characterized plant collections will be made available for
research by Center investigators and the broader research community.
Second, we will actively curate these medicinal plant germplasm collections at the North Central Regional
Plant Introduction Station (NCRPIS) as part of the US National Plant Germplasm System, along with all data
associated with their origins, taxonomic identities, and biochemical characteristics, which will be made
available via the Internet in the Germplasm Resources Information Network (GRIN) database.
Third, we will produce vegetative materials of known-source populations of these plants under controlled
conditions at the NCRPIS, through both field and controlled-environment culture, to serve as well-
characterized plant materials for the Center's research projects.
Fourth, we will conduct fingerprint analyses and chemical identification of the phytochemicals found in these
plants by conducting analytical research at Iowa State University's W.M. Keck Metabolomics Research
Laboratory.
And finally, we will survey the effects of environmental and developmental cues on the phytochemical
fingerprints of germplasm collections of Echinacea, Hypericum, Prunella, focusing on Prunella, where little is
known about the roles of environment and plant development on its chemical profiles.
These core activities provide valuable tools that allow researchers, who study the bioactive and toxic
components of these botanical supplements, methods for sorting out variation among plant species and
populations being used as sources for these supplements. This has been a complicating factor in the study
of all botanical supplements. By using known-source materials that are well characterized biochemically,
Center researchers can more efficiently identify bioactive components, and make recommendations that lead
to better clinical trials to maximize the human health benefits from these supplements while minimizing risks
to consumers.
爱荷华植物补充剂研究中心的核心A有五个长期目标来支持
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
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DIANE F BIRTH其他文献
DIANE F BIRTH的其他文献
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{{ truncateString('DIANE F BIRTH', 18)}}的其他基金
PAIN RECEPTOR MEDI ANTI-INFLAMMATORY ACTIV. OF ECHINACEA, HYPERICUM SPECIES/WURTE
疼痛受体药物抗炎活性。
- 批准号:
7293902 - 财政年份:2007
- 资助金额:
$ 24.77万 - 项目类别:
ANTI-INFLAMMATORY ACTIVITY OF ECHINACEA, HYPERICUM & PRUNELLA SPECIES/BIRT, DIANE
紫锥花、金丝桃的抗炎活性
- 批准号:
7293895 - 财政年份:2007
- 资助金额:
$ 24.77万 - 项目类别:
SEPARATIONS/STRUCTURE/BIOAVAILABILITY/KRAUS, GEORGE
分离/结构/生物利用度/KRAUS, GEORGE
- 批准号:
7293906 - 财政年份:2007
- 资助金额:
$ 24.77万 - 项目类别:
ADMINISTRATION, DATA MANAGEMENT, STATISTICS & BIOINFORMATICS/BIRT, DIANE
行政、数据管理、统计
- 批准号:
7293908 - 财政年份:2007
- 资助金额:
$ 24.77万 - 项目类别:
ANTI-INFLAMMATORY ACTIVITY OF ECHINACEA, HYPERICUM & PRUNELLA SPECIES/BIRT, DIANE
紫锥花、金丝桃的抗炎活性
- 批准号:
7634406 - 财政年份:
- 资助金额:
$ 24.77万 - 项目类别:
SEPARATIONS/STRUCTURE/BIOAVAILABILITY/KRAUS, GEORGE
分离/结构/生物利用度/KRAUS, GEORGE
- 批准号:
7634409 - 财政年份:
- 资助金额:
$ 24.77万 - 项目类别:
ADMINISTRATION, DATA MANAGEMENT, STATISTICS & BIOINFORMATICS/BIRT, DIANE
行政、数据管理、统计
- 批准号:
7869452 - 财政年份:
- 资助金额:
$ 24.77万 - 项目类别:
ANTI-INFLAMMATORY ACTIVITY OF ECHINACEA, HYPERICUM & PRUNELLA SPECIES/BIRT, DIANE
紫锥花、金丝桃的抗炎活性
- 批准号:
7869448 - 财政年份:
- 资助金额:
$ 24.77万 - 项目类别:
PAIN RECEPTOR MEDI ANTI-INFLAMMATORY ACTIV. OF ECHINACEA, HYPERICUM SPECIES/WURTE
疼痛受体药物抗炎活性。
- 批准号:
7869449 - 财政年份:
- 资助金额:
$ 24.77万 - 项目类别:
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