Analysis of RNA Dynamics Using 13C NMR Spin Relaxation Techniques

使用 13C NMR 自旋弛豫技术分析 RNA 动力学

• 批准号: 7414417
• 负责人: James Edward Johnson
• 金额: $ 1.45万
• 依托单位: MICHIGAN STATE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2007
• 资助国家: 美国
• 起止时间: 2007-05-16 至 2008-11-15
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7414417
• 关键词: Biological Models; Catalysis; Catalytic Domain; Catalytic RNA; Coupling; Data Analyses; Docking; Goals; Isotope Labeling; Label; Modeling; Molecular Conformation; Motion; Nuclear Magnetic Resonance; Nucleic Acids; Nucleotides; Pattern; RNA; RNA analysis; Relaxation; Relaxation Techniques; Research Project Grants; Ribonucleotides; Ribose; Roentgen Rays; Role; Scheme; Site; Structure; System; Therapeutic; Vertebral column; Work; base; design; hairpin ribozyme; insight; molecular dynamics; mutant; research study

项目成果

Extensive backbone dynamics in the GCAA RNA tetraloop analyzed using 13C NMR spin relaxation and specific isotope labeling.

• DOI: 10.1021/ja805759z
• 发表时间: 2008-12-10
• 期刊: JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
• 影响因子: 15
• 作者: Johnson, James E., Jr.;Hoogstraten, Charles G.
• 通讯作者: Hoogstraten, Charles G.