Genomics

描述(由申请人提供)：该提案请求支持加州大学伯克利分校(UCB)基因组学多学科项目的15名博士后和6名博士后学员。我们广义地将基因组学定义为获取和分析生物学中的高通量基因组规模的数据，并利用由此产生的数据来解决生物医学问题。UCB的20名参与教职员工来自9个系(分子和细胞生物学、物理学、化学、机械工程、综合生物学、公共卫生、营养学和计算机科学)。附近的劳伦斯伯克利国家实验室(LBNL)也有研究导师，该实验室是国家显微镜、成像、超级计算和同步辐射中心的所在地。学生可以在任何参与UCB部门的博士项目中被录取。 除了国内部门的严格培训外，还提供了范围广泛的教学课程，用于补充学科的培训，为学员提供接触基因组学技术开发、新技术可能攻击的重要生物和生物医学问题，以及分析和挖掘基因组数据的计算方法的机会。受训者通常会在加州大学伯克利分校或LBNL的不同研究环境中选择不同的实验室，轮流工作三个连续十周的时间。每个学员的具体多学科课程将在咨询两位教师导师的意见后选择，其中一位来自生物学，一位来自物理科学或工程。学生通常在第二年结束时参加口语资格考试，并开始从事研究项目。在3-5年级，学员进行论文研究，继续教授和参加高级课程，并参加研讨会、小组会议和静修以扩大他们的技能。 申请者通常在生物、化学、物理科学或工程学方面拥有优异的本科成绩。录取依据是对以前的学术成就、以前的研究经验和表现、标准化考试的分数、目的声明和推荐信的评估。

DESCRIPTION (provided by applicant): The proposal requests support for fifteen predoctoral and six postdoctoral trainees in a multidisciplinary program in Genomics at the University of California, Berkeley (UCB). We define Genomics broadly as the acquisition and analysis of high-throughput genome-scale data in biology, and the exploitation of the resulting data to solve biomedical problems. The 20 participating faculty at UCB are drawn from nine Departments (Molecular and Cell Biology, Physics, Chemistry, Mechanical Engineering, Integrative Biology, Public Health, Nutrition, and Computer Science). Research mentors are also available at the nearby Lawrence Berkeley National Laboratory (LBNL), which is home to national centers for microscopy, imaging, supercomputing, and synchrotron radiation. Students can be admitted to the program throughout the Ph.D. programs of any of the participating UCB departments. In addition to rigorous training in their home departments, a wide range of didactic courses are available for training in complementary disciplines to provide trainees with exposure to technology development for Genomics, important biological and biomedical problems that can be attacked by new technologies, and computational approaches to analysis and mining of genomic data. Trainees typically spend three consecutive ten-week periods rotating through different laboratories of their choice selected from a diverse array of research environments at UC Berkeley or at LBNL. The specific multidisciplinary course of study for each trainee will be chosen in consultation with a pair of faculty mentors, one from biology and one from the physical sciences or engineering. Students typically take their oral qualifying exams by the end of the second year, and begin to engage in research projects. In years 3-5 trainees carry out their dissertation research, continue to teach and take advanced courses, and participate in seminars, group meetings, and retreats to expand their skills. Applicants to the participating departments typically have outstanding undergraduate records in the biological, chemical, or physical sciences, or engineering. Admission is based on evaluation of previous scholastic achievement, prior research experience and performance, scores on standardized exams, statement of purpose, and letters of recommendation.