Genomics

描述（由申请人提供）：该提案要求在加州大学伯克利分校（UCB）的基因组学多学科计划中支持15名博士前和6名博士后学员。我们将基因组学广义地定义为生物学中高通量基因组规模数据的获取和分析，以及对所得数据的利用以解决生物医学问题。UCB的20名参与教师来自9个部门（分子和细胞生物学，物理，化学，机械工程，综合生物学，公共卫生，营养和计算机科学）。附近的劳伦斯伯克利国家实验室（LBNL）也有研究导师，该实验室是国家显微镜，成像，超级计算和同步辐射中心的所在地。学生可以被录取到整个博士课程。任何参与UCB部门的计划。 除了在他们的家庭部门严格的培训外，广泛的教学课程可用于补充学科的培训，为学员提供接触基因组学技术开发，可能受到新技术攻击的重要生物和生物医学问题，以及分析和挖掘基因组数据的计算方法。学员通常会连续三个十周的时间，轮流通过他们选择的不同实验室，这些实验室是从加州大学伯克利分校或LBNL的各种研究环境中选出的。每个学员的具体多学科课程将与一对教师导师协商选择，一个来自生物学，一个来自物理科学或工程学。学生通常在第二年年底参加口试，然后开始从事研究项目。在3-5年的实习生进行论文研究，继续教学和高级课程，并参加研讨会，小组会议和务虚会，以扩大他们的技能。 申请人参加部门通常在生物，化学或物理科学，或工程优秀的本科记录。录取是基于以前的学业成绩，以前的研究经验和表现，标准化考试的分数，目的声明和推荐信的评估。

DESCRIPTION (provided by applicant): The proposal requests support for fifteen predoctoral and six postdoctoral trainees in a multidisciplinary program in Genomics at the University of California, Berkeley (UCB). We define Genomics broadly as the acquisition and analysis of high-throughput genome-scale data in biology, and the exploitation of the resulting data to solve biomedical problems. The 20 participating faculty at UCB are drawn from nine Departments (Molecular and Cell Biology, Physics, Chemistry, Mechanical Engineering, Integrative Biology, Public Health, Nutrition, and Computer Science). Research mentors are also available at the nearby Lawrence Berkeley National Laboratory (LBNL), which is home to national centers for microscopy, imaging, supercomputing, and synchrotron radiation. Students can be admitted to the program throughout the Ph.D. programs of any of the participating UCB departments. In addition to rigorous training in their home departments, a wide range of didactic courses are available for training in complementary disciplines to provide trainees with exposure to technology development for Genomics, important biological and biomedical problems that can be attacked by new technologies, and computational approaches to analysis and mining of genomic data. Trainees typically spend three consecutive ten-week periods rotating through different laboratories of their choice selected from a diverse array of research environments at UC Berkeley or at LBNL. The specific multidisciplinary course of study for each trainee will be chosen in consultation with a pair of faculty mentors, one from biology and one from the physical sciences or engineering. Students typically take their oral qualifying exams by the end of the second year, and begin to engage in research projects. In years 3-5 trainees carry out their dissertation research, continue to teach and take advanced courses, and participate in seminars, group meetings, and retreats to expand their skills. Applicants to the participating departments typically have outstanding undergraduate records in the biological, chemical, or physical sciences, or engineering. Admission is based on evaluation of previous scholastic achievement, prior research experience and performance, scores on standardized exams, statement of purpose, and letters of recommendation.