Pediatric Rheumatology Training Grant

描述(由申请人提供)： 这项培训拨款提案寻求支持，使个人(医学博士、医学博士或博士)为从事与儿科和成人风湿病相关的生物医学科学做好准备。该计划的基础是风湿病(儿科)的一个大部门，有几个中心拨款(P30，P60，PO1)和NIH资助的研究人员，还有一个扩大的风湿病(成人)部门的参与，该部门也有强大的NIH资金。儿科及其相关诊所是辛辛那提儿童医院医疗中心(CCHMC)和儿童医院研究基金会(TCHRF)的一部分，也是辛辛那提大学医学院(UCCOM)及其临床和生物医学科学系的一部分。成人部是加州大学洛杉矶分校医学部的一部分，与儿科分部以及CCHMC和UCCOM的免疫生物学研究人员有着密切的联系。主要的教师顾问不仅来自儿科(风湿学、过敏/免疫学、实验血液学、血液学/肿瘤学、人类遗传学、免疫生物学、信息学、分子免疫学和心理学)和医学系(免疫学和传染病)的部门，而且还来自环境卫生和病理学系，涵盖了广泛的专业领域。这些学科包括免疫生物学、基因组学和生物信息学、基因表达、分子和发育生物学、基因治疗、干细胞生物学、流行病学家和生物统计学，以及肌肉骨骼生物力学。除了儿科风湿学方面的持续发展外，CCHMC、UCCOM和TCHRF在目前的五年培训资助周期中也有相当大的增长，特别是在免疫生物学、实验血液学和生物信息学方面。该计划得到了核心设施以及学术课程的良好支持，其中包括一门医德必修课。其他可用的课程包括免疫生物学、分子遗传学、流行病学和生物统计学。一个新的以CCHMC为中心的跨部门免疫生物学研究生课程(MS和PHD)是对现有的流行病学和生物统计学以及UCCOM教育课程的补充。据信，这个风湿学项目提供了独特的资源，并将继续扩大对生物医学科学有职业兴趣的个人池，因为它与子专科相关，随着分子医学在临床上的应用越来越多，这个池太小了，无法满足未来几十年的要求。

DESCRIPTION (provided by applicant): This training grant proposal seeks support to prepare individuals (MD, MD/PhD, or PhD) for a career in biomedical science as it relates to pediatric and adult rheumatology. The program is based in a large Division of Rheumatology (Pediatric), with several center grants (P30, P60, PO1) and NIH-funded investigators with the participation of an enlarging Division of Rheumatology (Adult) that also has strong NIH funding. The Pediatric Division, including its related clinic, is part of Cincinnati Children's Hospital Medical Center (CCHMC) and The Children's Hospital Research Foundation (TCHRF), as well as part of the University of Cincinnati College of Medicine (UCCOM) with its clinical and biomedical science departments. The Adult Division is part of the Department of Medicine of UCCOM and has strong ties to the Pediatric Division and to immunobiology researchers at CCHMC and UCCOM. The primary faculty advisors come not only from divisions within the Department of Pediatrics (Rheumatology, Allergy/Immunology, Experimental Hematology, Hematology/Oncology, Human Genetics, Immunobiology, Informatics, Molecular Immunology, and Psychology) and the Department of Medicine (Immunology and Infectious Disease) but also from the Departments of Environmental Health, and Pathology, and cover broad areas of expertise. These include immunobiology, genomics and bioinformatics, gene expression, molecular and developmental biology, gene therapy, stem cell biology, epidemiologist and biostatistics, and musculoskeletal biomechanics. In addition to continued expansion in pediatric rheumatology, CCHMC, UCCOM, and TCHRF have also seen considerable growth during the present five-year cycle of this training grant, particularly in immunobiology, experimental hematology, and bioinformatics. The program is well supported by core facilities as well as by academic courses, including a mandatory course in medical ethics. Other available courses include immunobiology, molecular genetics, and epidemiology and biostatistics. A new interdepartmental Immunobiology Graduate Program (MS and PhD) that is centered at CCHMC complements existing programs in Epidemiology and Biostatistics, and Education in the UCCOM. It is believed that this rheumatology program provides unique resources and will continue to enlarge the pool of individuals with a career interest in biomedical science as it relates to the subspecialties, a pool that is far too small to meet the requirements of the next decades as molecular medicine is increasingly applied in the clinic.