CORE--Operations

运营部门将监督行政和财政活动，保护人类受试者，实施NIH数据共享政策，临床试验管理，药物监测，数据库管理，生物统计咨询和服务，研究培训，研究伦理咨询以及向医疗保健提供者，消费者和家庭传播信息。为了促进ACISR/LLMD的活动，这些职能 将由四个单位执行和整合： 1.行政单位将管理中心资源的分配，执行政策，并促进与社区合作伙伴的沟通。行政单位的主要组成部分将包括种子资金计划，外部和内部科学咨询委员会，董事会的研究合作伙伴和执行委员会。关于支持哪些项目的决定将与社区研究伙伴协商作出。行政单位还将：1）促进前和博士后的研究职业发展 研究员和初级教师学者; 2）提供研究伦理咨询; 3）提供 就接触目标受众的战略进行咨询，与执业临床医生进行外联，并与消费者和家庭进行外联。2.临床试验管理部门（CTMU）将为预防、干预和康复研究的操作方面提供咨询和服务，包括研究中心招募、受试者招募、保留、评估、随访和跨研究中心协调。3.药物监测单位将为ACISR/LLMD临床试验的药物部分提供咨询和服务。4.方法学、生物统计学和数据管理股将提供从研究概念化到手稿准备的方法学问题方面的培训、咨询和服务，包括研究设计、数据管理、数据分析和解释。它还将涉及数据存储，访问和安全性。这些单位将参与研究开发、实施和报告的各个方面，以支持ACISR/LLMD的使命，即改善科学数据库并增强老年人情感障碍护理的真实的世界实践（即，连接科学和服务）。

Operations will oversee administrative and fiscal activities, protection of human subjects, implementation of NIH data sharing policies, clinical trials management, medication monitoring, data base administration, biostatistical consultation and services, research training, consultation in research ethics, and information dissemination to healthcare providers, consumers, and families. In order to facilitate activity of the ACISR/LLMD, these functions will be carried out and integrated by four units: 1. The Administrative Unit will manage allocation of center resources, implement policies, and foster communication with community partners. Key components of the Administrative Unit will include the Seed Money program, the External and Internal Scientific Advisory Committees, the Research Partners Board of Directors, and the Executive Committee. Decisions about which projects to support will be made in consultation with community research partners. The Administrative Unit will also: 1) foster the research career development of pre- and postdoctoral fellows and of junior faculty scholars; 2) provide consultation in research ethics; and 3) provide consultation on strategies for reaching intended audiences, outreach to practicing clinicians, and outreach to consumers and families. 2. The Clinical Trials Management Unit (CTMU) will provide consultation and services for operational aspects of prevention, intervention, and rehabilitation research, including site recruitment, subject recruitment, retention, assessment, follow-up, and cross-site co-ordination. 3. The Medication Monitoring Unit will provide consultation and services for the pharmacotherapeutic component of clinical trials in the ACISR/LLMD. 4. The Methodology, Biostatistics and Data Management Unit will offer training, consultation, and services regarding methodologic issues from study conceptualization through manuscript preparation, including research design, data management, and data analysis and interpretation. It will also be concerned with data storage, access, and security. These units will be involved in all aspects of study development, implementation, and reporting in order to support the mission of the ACISR/LLMD, which is to improve the scientific database and enhance real world practice in the care of elderly living with mood disorders (i.e, to bridge science and service).